RAD51C and SWSAP1

Number of citations of the paper that reports this interaction (PubMedID 21965664)
37

Data Source:
BioGRID (affinity chromatography technology, pull down)

		RAD51C	SWSAP1
Description		RAD51 paralog C	SWIM-type zinc finger 7 associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Cytosol Cell Junction Rad51B-Rad51C-Rad51D-XRCC2 Complex Rad51C-XRCC3 Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Shu Complex
	Molecular Function	Four-way Junction DNA Binding DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Crossover Junction Endodeoxyribonuclease Activity	Single-stranded DNA Binding Protein Binding ATP Hydrolysis Activity
	Biological Process	Meiotic DNA Recombinase Assembly Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Sister Chromatid Cohesion Female Meiosis Sister Chromatid Cohesion Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Double-strand Break Repair Via Homologous Recombination Protein Stabilization
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Meiotic recombination Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Cognitive function ( 25644384) Primary tooth development (time to first tooth eruption) ( 23704328) Testicular germ cell tumor ( 23666239 23666240)	Coronary artery disease ( 29212778)
Interacting Genes		9 interacting genes: APP GATA3 PALB2 RAD51 RAD51B RAD51D SPG21 SWSAP1 XRCC3	9 interacting genes: A2M EPM2AIP1 RAD51 RAD51B RAD51C RAD51D SPG21 XRCC3 ZSWIM7
Entrez ID		5889	126074
HPRD ID		04143	08179
Ensembl ID		ENSG00000108384	ENSG00000173928
Uniprot IDs		O43502	Q6NVH7
PDB IDs
Enriched GO Terms of Interacting Partners?
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