SWSAP1 and XRCC3

Number of citations of the paper that reports this interaction (PubMedID 21965664)
37

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SWSAP1	XRCC3
Description		SWIM-type zinc finger 7 associated protein 1	X-ray repair cross complementing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Shu Complex	Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Cytosol Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Single-stranded DNA Binding Protein Binding ATP Hydrolysis Activity	Four-way Junction DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Crossover Junction Endodeoxyribonuclease Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Protein Stabilization	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus Response To Organic Substance Regulation Of Centrosome Duplication Interstrand Cross-link Repair Double-strand Break Repair Via Synthesis-dependent Strand Annealing Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint T-circle Formation Telomeric Loop Disassembly Telomere Maintenance Via Telomere Trimming
Pathways			HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 26426971 29273807) Schizophrenia ( 25056061 29483656)
Interacting Genes		9 interacting genes: A2M EPM2AIP1 RAD51 RAD51B RAD51C RAD51D SPG21 XRCC3 ZSWIM7	22 interacting genes: BAP1 BCAS3 CXCL1 FANCG GREB1 ITIH5 LRATD2 MRC2 OSGIN1 PALB2 PSMC3IP RAD51 RAD51C RAD51D RNF20 SCGB3A1 SERPINB5 SNAI1 SWSAP1 TFF1 ZNHIT3 ZSWIM7
Entrez ID		126074	7517
HPRD ID		08179	07201
Ensembl ID		ENSG00000173928	ENSG00000126215
Uniprot IDs		Q6NVH7	O43542 Q53XC8
PDB IDs
Enriched GO Terms of Interacting Partners?
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