BBS1 and EIF3A

Number of citations of the paper that reports this interaction (PubMedID 18000879)
7

Data Source:
BioGRID (two hybrid)

		BBS1	EIF3A
Description		Bardet-Biedl syndrome 1	eukaryotic translation initiation factor 3 subunit A
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GO Annotations	Cellular Component	Centrosome Cytosol Axoneme BBSome Ciliary Basal Body Ciliary Membrane	Nucleoplasm Nucleolus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Microtubule Postsynaptic Density Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Multi-eIF Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3e Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Patched Binding Smoothened Binding Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Binding MRNA Binding Translation Initiation Factor Activity Structural Molecule Activity Protein Binding Receptor Tyrosine Kinase Binding
	Biological Process	Visual Perception Sensory Perception Of Smell Golgi To Plasma Membrane Protein Transport Photoreceptor Cell Maintenance Response To Stimulus Cilium Assembly Protein Localization To Cilium Non-motile Cilium Assembly	Formation Of Cytoplasmic Translation Initiation Complex Translation Reinitiation Translational Initiation Negative Regulation Of ERK1 And ERK2 Cascade IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation
Pathways		BBSome-mediated cargo-targeting to cilium	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Height ( 28552196)	Alcoholic chronic pancreatitis ( 28754779) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Keratoconus ( 33649486) Plateletcrit ( 32888494)
Interacting Genes		19 interacting genes: ACTN3 ATP6AP2 BAD BAK1 BHMT CALCA DCTN1 EEF1A1 EIF3A EPAS1 EXOC7 FHOD1 HSCB KRT18 PARK7 PAX2 PEPD POLR2G TSPAN7	24 interacting genes: BBS1 BBS4 BZW2 CACNA1A EIF3B EIF3G EIF3I EIF3J EIF4B EIF4G1 EIF4G2 FXR1 LAMTOR5 LINC01554 MTNR1B PAIP1 REL RNF139 SRPK2 TFIP11 TSC1 UBC UPF1 YWHAZ
Entrez ID		582	8661
HPRD ID		01950	03618
Ensembl ID		ENSG00000174483	ENSG00000107581
Uniprot IDs		Q8NFJ9	Q14152
PDB IDs		6XT9	3J8B 3J8C 6YBD 6YBT 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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