NECTIN2 and KRTAP10-5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		NECTIN2	KRTAP10-5
Description		nectin cell adhesion molecule 2	keratin associated protein 10-5
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Cell Surface Integral Component Of Membrane Apical Junction Complex Cell-cell Contact Zone Extracellular Exosome	Cytosol Keratin Filament
	Molecular Function	Virus Receptor Activity Protein Binding Coreceptor Activity Identical Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding	Protein Binding Identical Protein Binding
	Biological Process	Acrosome Assembly Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immunoglobulin Mediated Immune Response Cytoskeleton Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Spermatid Development Spermatid Nucleus Differentiation Fertilization Fusion Of Virus Membrane With Host Plasma Membrane Sperm Mitochondrion Organization Cell Part Morphogenesis Positive Regulation Of Mast Cell Activation Susceptibility To Natural Killer Cell Mediated Cytotoxicity Adhesion Of Symbiont To Host Cilium Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Viral Entry Into Host Cell Coreceptor-mediated Virion Attachment To Host Cell Positive Regulation Of T Cell Receptor Signaling Pathway Establishment Of Mitochondrion Localization Susceptibility To T Cell Mediated Cytotoxicity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 30498476) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Urate levels ( 31578528)
Interacting Genes		37 interacting genes: AFDN ATP5MF CD226 CYSRT1 DUS2 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP5-9 LCE1C LCE2B LCE2C LCE5A LYRM4 MAPK6 MDFI MEOX2 NBPF19 NECTIN3 NECTIN4 NOTCH2NLA NR4A3 P4HB PICK1 PVR RGS20 SIAH1 TCF4 TGM1 TIGIT USP53	143 interacting genes: ADAMTSL4 AEN ALDH3B1 AMOTL2 BCL6B BMP7 BYSL C11orf87 C17orf50 CARD9 CATSPER1 CHRD CNNM3 CREB5 CYSRT1 DHX57 ECE1 EIF4E2 ENKD1 FAM74A4 FAM76B FARS2 FBXO34 FCHO1 GATA1 GLIDR GLRX3 GNE GOLGA8EP GPRIN2 HHEX HOXA1 HPCAL1 KRTAP1-3 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-1 KRTAP13-2 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1B LCE1C LCE1D LCE1E LCE2A LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LIMS2 LUZP4 MEOX2 MOBP MT1DP MXI1 NAA10 NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR4A1 NR4A3 NTAQ1 NUFIP2 OTX1 POM121L8P POU4F2 PRKAB2 PRKAG1 PRR13 RBP3 SCNM1 SHFL SLC23A1 SLC6A20 SMCP SPACA9 SPATA3 SPRY1 SPRY2 STK16 TBC1D16 THAP10 TNP2 TNS2 TRIM42 TRPV6 TULP3 TXNDC5 TYMSOS UTP23 WT1 WT1-AS YY1 ZBTB24 ZBTB48 ZFYVE21 ZNF124 ZNF20 ZNF264 ZNF273 ZNF286A ZNF32 ZNF320 ZNF329 ZNF34 ZNF417 ZNF433 ZNF439 ZNF440 ZNF559 ZNF572 ZNF578 ZNF587 ZNF670 ZNF679 ZNF696 ZNF697 ZNF707 ZNF785 ZNF792 ZSCAN21 ZSCAN26
Entrez ID		5819	386680
HPRD ID		02879	11191
Ensembl ID		ENSG00000130202	ENSG00000241123
Uniprot IDs		Q92692
PDB IDs		3R0N 4DFH 4DFI 4HZA 5V52
Enriched GO Terms of Interacting Partners?
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