PTPRD and NEK2

  • Number of citations of the paper that reports this interaction (PubMedID 22305495)
  • 17

PTPRD

NEK2

Description protein tyrosine phosphatase receptor type D NIMA related kinase 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Airflow obstruction ( 22837378)
  • Anxiety and major depressive disorder ( 24047446)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease ( 28044437)
  • Cardiac Troponin-T levels ( 31014085)
  • Cardiorespiratory fitness (800m run time) ( 32572135)
  • Cerebrospinal P-tau181p levels ( 28247064)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653)
  • Early age at menarche ( 29773799)
  • Endometrial cancer (endometrioid histology) ( 30093612)
  • Endometriosis or endometrial cancer (pleiotropy) ( 29608257)
  • Epilepsy (remission after treatment) ( 23962720)
  • Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243)
  • Gait rhythm ( 26219847)
  • Glycine levels ( 31070104)
  • Gout ( 22179738)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Heel bone mineral density ( 30598549)
  • Immune response to measles-mumps-rubella vaccine ( 24811271)
  • Intracranial aneurysm ( 29531279)
  • Lean body mass ( 28552196)
  • Loneliness ( 27629369)
  • Loneliness (linear analysis) ( 27629369)
  • Loneliness (multivariate analysis) ( 27629369)
  • Low susceptibility to hepatitis C infection ( 31206233)
  • Menarche (age at onset) ( 29773799 25231870)
  • Metabolite levels ( 23823483)
  • Midgestational circulating levels of PCBs (fetal genetic effect) ( 28235828)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Modic changes ( 30808802)
  • Mood instability ( 29187730)
  • Morning person ( 30696823)
  • Myopia (pathological) ( 23049088)
  • Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)
  • Non-response to antidepressants and depression ( 27622933)
  • Obesity-related traits ( 23251661)
  • Obsessive-compulsive disorder ( 24821223)
  • Obsessive-compulsive traits ( 33531474)
  • Opioid use cessation ( 31936517)
  • Palmitic acid (16:0) levels ( 23362303)
  • Parkinson's disease progression (motor) ( 33111402)
  • Partial epilepsies ( 20522523)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Personality dimensions ( 23903073)
  • Pit-and-Fissure caries ( 24556642)
  • Plasma clusterin levels ( 26545630)
  • Platelet aggregation ( 20526338)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1 in COPD ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Pulse pressure ( 27841878)
  • Pursuit maintenance gain ( 29064472)
  • Resistant hypertension ( 30237584)
  • Resting-state electroencephalogram vigilance ( 29703947)
  • Restless legs syndrome ( 33239738 18660810 29029846 21779176)
  • Short-term memory (digit-span task) ( 30741946)
  • Smoking initiation ( 33082346)
  • spontaneous preterm birth x maternal stress interaction (1df) ( 32726798)
  • Subcutaneous adipose tissue ( 26480920)
  • Systolic blood pressure ( 30224653 27841878)
  • Temperament ( 22832960)
  • Third ventricle volume ( 31530798)
  • Triglyceride levels ( 34074324)
  • Triglyceride levels in HIV infection ( 33109212)
  • Type 2 diabetes ( 21647700 20174558)
  • Waist-hip ratio ( 28552196)
  • Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
  • White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes 35 interacting genes: ABLIM1 AURKA BMX CSNK1D CSNK1E DDX17 DDX54 EPHA8 GPC4 IL1RAP IRS1 MARK2 MATK MTNR1A MTNR1B MTSS1 NEK1 NEK2 NEK6 PAK6 PLK1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS SCEL SLAIN2 SLITRK1 SMTNL2 TBK1 TRAFD1 TSSK2 41 interacting genes: ADORA1 ARHGEF11 ATF3 CCDC85A CD46 CDC20 CEP250 CHGA CNTN2 CSN2 CTNNB1 DCTN1 DUSP10 EDRF1 EIF4A2 FLVCR1 FZR1 GIT1 IFT140 IMMT KCNA4 KIAA0930 MAD1L1 MAPK1 MCC NDC80 NEK11 NENF PDE4DIP PLCB2 PPP1CA PPP1CC PPP1R2 PPP2R5A PRKN PROX1 PTPRD SMURF1 SPTBN4 TCF25 TPM3
Entrez ID 5789 4751
HPRD ID 03358 04953
Ensembl ID ENSG00000153707 ENSG00000117650
Uniprot IDs P23468 Q2HXI4 Q3KPI9 Q59H90 F6U4U2 P51955
PDB IDs 1X5Z 2DLH 2YD6 2YD7 4RCA 5WY8 5XNP 2JAV 2W5A 2W5B 2W5H 2WQO 2XK3 2XK4 2XK6 2XK7 2XK8 2XKC 2XKD 2XKE 2XKF 2XNM 2XNN 2XNO 2XNP 4A4X 4AFE 5M51 5M53 5M55 5M57 6SGD 6SGH 6SGI 6SGK 6SK9 6TM5
Enriched GO Terms of Interacting Partners?
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