NEK2 and CEP250

  • Number of citations of the paper that reports this interaction (PubMedID 9647649)
  • 160
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, two hybrid, in vitro)

NEK2

CEP250

Description NIMA related kinase 2 centrosomal protein 250
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Brain morphology (MOSTest) ( 32665545)
  • Height ( 25429064 18391951)
  • Hip circumference adjusted for BMI ( 34021172)
  • Refractive error ( 32231278)
  • Ulcerative colitis ( 23128233)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 41 interacting genes: ADORA1 ARHGEF11 ATF3 CCDC85A CD46 CDC20 CEP250 CHGA CNTN2 CSN2 CTNNB1 DCTN1 DUSP10 EDRF1 EIF4A2 FLVCR1 FZR1 GIT1 IFT140 IMMT KCNA4 KIAA0930 MAD1L1 MAPK1 MCC NDC80 NEK11 NENF PDE4DIP PLCB2 PPP1CA PPP1CC PPP1R2 PPP2R5A PRKN PROX1 PTPRD SMURF1 SPTBN4 TCF25 TPM3 14 interacting genes: APP ATF7IP FAM83D FRMD5 ITCH KAT2B KCNG3 MYL9 NEK2 PDIA6 PHF20 PLEKHA5 TTI1 YWHAG
Entrez ID 4751 11190
HPRD ID 04953 09877
Ensembl ID ENSG00000117650 ENSG00000126001
Uniprot IDs F6U4U2 P51955 Q9BV73
PDB IDs 2JAV 2W5A 2W5B 2W5H 2WQO 2XK3 2XK4 2XK6 2XK7 2XK8 2XKC 2XKD 2XKE 2XKF 2XNM 2XNN 2XNO 2XNP 4A4X 4AFE 5M51 5M53 5M55 5M57 6SGD 6SGH 6SGI 6SGK 6SK9 6TM5 6OQA
Enriched GO Terms of Interacting Partners?
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