CCDC146 and MED4

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 484
  • Data Source:
  • BioGRID (two hybrid)

CCDC146

MED4

Description coiled-coil domain containing 146 mediator complex subunit 4
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 28892062)
  • Macrovascular complications in type 2 diabetes ( 33430853)
  • Ophthalmic complications in type 2 diabetes ( 33430853)
  • Response to amphetamines ( 22952603)
  • Proportion of activated microglia (inferior temporal cortex) ( 30679421)
  • Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122)
  • Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
  • Thiopurine-induced early leukopenia in Crohn's disease ( 25108385)
  • Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122)
  • Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122)
  • Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122)
Interacting Genes 71 interacting genes: AKAP9 BLOC1S2 CBY2 CCDC136 CCDC197 CCNDBP1 CDR2 CDR2L CENPH CEP170P1 CEP44 DTNBP1 FSD2 GAS8 GMNN GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 HSF2BP INSYN1 KIFC3 KRT16 KRT18 KRT19 KRT24 KRT26 KRT27 KRT31 KRT34 KRT38 KRT40 KRT86 LHX3 MAGEA11 MAGEA6 MCC MED4 MIPOL1 MRFAP1 MTUS2 N4BP3 NAP1L2 NECAB2 NINL NUP62 PDE4DIP PLEKHF2 PNMA1 PPP2R3C PROSER3 PSMC6 RINT1 RNF40 RPGRIP1 SH3BP1 SYCE1L TEPSIN TFIP11 THOC7 TNR TPM3 TRAF1 TRIM23 TRIM54 TRIML2 TSC22D4 TXLNA USHBP1 VPS28 VPS52 41 interacting genes: AMOT AP2M1 ATF7IP ATF7IP2 C1orf216 CCDC146 CCHCR1 CTDP1 CTNNBL1 FAM13C FOXJ3 FRMD6 FTCD GCC1 HAUS1 HGS IP6K3 KIFC3 LRRFIP1 MAB21L3 MCRS1 MED30 MED9 NDE1 OIP5 PCBD2 PUM2 SDCBP SDCBP2 SGF29 SMARCD1 SMARCE1 SSX3 SYCE2 TLE5 TNFAIP8 TNFAIP8L1 TXLNA TXLNB USHBP1 WDTC1
Entrez ID 57639 29079
HPRD ID 11150 16145
Ensembl ID ENSG00000135205 ENSG00000136146
Uniprot IDs Q8IYE0 Q96MS1 A0A024RDY7 Q9NPJ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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