ISLR2 and LAPTM4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ISLR2	LAPTM4B
Description		immunoglobulin superfamily containing leucine rich repeat 2	lysosomal protein transmembrane 4 beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Multivesicular Body Membrane Cell Projection Multivesicular Body, Internal Vesicle
	Molecular Function	Protein Binding	Protein Binding Kinase Binding Ubiquitin Protein Ligase Binding Ceramide Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Positive Regulation Of Axon Extension	Endosome Organization Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Regulation Of Lysosomal Membrane Permeability Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Metabolite levels ( 23823483) QT interval ( 24952745)
Interacting Genes		6 interacting genes: EMP1 LAPTM4B MRAP2 NKG7 STRIT1 UPK1B	22 interacting genes: BDKRB1 CGRRF1 CTXN3 CYB561A3 EMP1 GJA8 GPX8 IFNAR1 IGFBP5 ISLR2 MTIF3 NAALADL2 NRG1 ODF4 PIP5K1C SCARB2 SLC22A1 SLC22A2 SLC29A2 TMEM67 TMEM86B TRARG1
Entrez ID		57611	55353
HPRD ID		13865	13960
Ensembl ID		ENSG00000167178	ENSG00000104341
Uniprot IDs		Q6UXK2	Q86VI4
PDB IDs
Enriched GO Terms of Interacting Partners?
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