ISLR2 and MRAP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ISLR2	MRAP2
Description		immunoglobulin superfamily containing leucine rich repeat 2	melanocortin 2 receptor accessory protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Regulator Activity Corticotropin Hormone Receptor Binding Type 3 Melanocortin Receptor Binding Type 4 Melanocortin Receptor Binding Type 5 Melanocortin Receptor Binding Identical Protein Binding Type 1 Melanocortin Receptor Binding
	Biological Process	Positive Regulation Of Axon Extension	Energy Reserve Metabolic Process Feeding Behavior Protein Localization To Plasma Membrane Energy Homeostasis Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)	Schizophrenia ( 28991256) Whole brain grey matter density ( 31530798)
Interacting Genes		6 interacting genes: EMP1 LAPTM4B MRAP2 NKG7 STRIT1 UPK1B	6 interacting genes: APH1A APP ISLR2 MC2R SGTA TMEM80
Entrez ID		57611	112609
HPRD ID		13865	12843
Ensembl ID		ENSG00000167178	ENSG00000135324
Uniprot IDs		Q6UXK2	Q96G30
PDB IDs
Enriched GO Terms of Interacting Partners?
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