HACE1 and UBE2L3

  • Number of citations of the paper that reports this interaction (PubMedID 29643511)
  • 50
  • Data Source:
  • BioGRID (pull down, pull down, enzymatic study)

HACE1

UBE2L3

Description HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 ubiquitin conjugating enzyme E2 L3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • Age at voice drop ( 27182965)
  • Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
  • Feeling guilty ( 29500382)
  • Height ( 18391951)
  • Hip circumference adjusted for BMI ( 34021172)
  • Intraocular pressure ( 29617998)
  • Major depressive disorder ( 27479909)
  • Menarche (age at onset) ( 19448622 27182965)
  • Multiple sclerosis ( 23412934)
  • Neuroblastoma ( 22941191)
  • Obsessive-compulsive disorder ( 22889921)
  • Resistant hypertension ( 31545351)
  • Schizophrenia ( 28991256)
  • Sporadic neuroblastoma ( 28545128)
  • Thyroid stimulating hormone levels ( 17903292)
  • Type 2 diabetes ( 31049640)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in inactive individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes 9 interacting genes: MTDH OPTN PAK1 PLXNA2 RAB4A RAC1 SNTG2 UBE2D2 UBE2L3 109 interacting genes: ANKIB1 AREL1 ARIH1 ARIH2 ATXN3 BRAP BRCA1 CBL CBLB CBLC CCNB1IP1 CDC42 CDKN1B CUL9 DTX3 FBXO2 FOS HACE1 HECTD1 HECTD2 HECTD4 HECW1 HECW2 HERC1 HERC2 HERC3 HERC4 HERC6 HSPA4 HUWE1 IRF2BP1 ITCH LIG4 LTN1 MAPK6 MDM2 MEX3A MEX3C MID1 MKRN2 MKRN3 MUL1 MYCBP2 NEDD4 NEDD4L NFKBIA NR3C1 OTUB1 OTUD3 PIAS1 PIAS2 PJA1 POLR2A PRKN PTEN RBCK1 RBX1 RC3H1 RELA RNF103 RNF113B RNF114 RNF125 RNF14 RNF144A RNF144B RNF150 RNF168 RNF170 RNF182 RNF19A RNF19B RNF2 RNF20 RNF213 RNF216 RNF220 RNF31 RNF7 RTF2 SMAD4 SMAD7 SMURF1 SMURF2 STUB1 TP53 TRAF6 TRAF7 TRIM21 TRIM23 TRIM25 TRIM28 TRIM31 TRIM39 TRIM55 TRIP12 UBA1 UBA5 UBA6 UBA7 UBASH3A UBE3A UBE3C UBOX5 UBR4 UBR5 VPS11 WWP1 WWP2
Entrez ID 57531 7332
HPRD ID 17086 04762
Ensembl ID ENSG00000085382 ENSG00000185651
Uniprot IDs Q8IYU2 A0A024R1A4 P68036
PDB IDs 1C4Z 1FBV 3SQV 3SY2 4Q5E 4Q5H 5HPT 5TTE 5UDH 6CP2 6DJW 6DJX 6N13 6XXU 7B5L 7B5N
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?