RPTOR and MARK4

  • Number of citations of the paper that reports this interaction (PubMedID 23184942)
  • 22
  • Data Source:
  • BioGRID (enzymatic study)

RPTOR

MARK4

Description regulatory associated protein of MTOR complex 1 microtubule affinity regulating kinase 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Hypertension ( 30487518)
  • Mean arterial pressure ( 30487518)
  • NASH resolution in nonalcoholic steatohepatitis ( 31832568)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity ( 23563607)
  • Pulse pressure ( 29403010 30487518)
  • Systolic blood pressure ( 30487518)
Interacting Genes 30 interacting genes: BAHCC1 CBX8 CCDC40 CILK1 DCXR DUXAP9 EIF4EBP1 EIF4EBP2 IRS1 IRS2 LINC00839 MAPK1 MAPK3 MARK4 MLST8 MTOR NRBF2 PLD2 PRKAA1 PRKAA2 RAP1B RHEB RNF213 RPS6KA1 RPS6KB1 RRAGB TNRC6C USP36 WDR45B WIPI2 30 interacting genes: APLNR CDC42 HGS HNRNPK HPS6 KHDRBS3 KRT31 KRT40 MAP2 MAP4 MAPT MED20 MTUS2 NEDD4 NOTCH2NLA ODF2 PARD6A PNMA1 PRKCG PRKCI PRNP PTBP1 RPTOR STK11 TUBA4A TUBB TUBG1 YWHAB YWHAH YWHAZ
Entrez ID 57521 57787
HPRD ID 06184 09402
Ensembl ID ENSG00000141564 ENSG00000007047
Uniprot IDs Q6DKI0 Q8N122 Q96L34
PDB IDs 5H64 6BCU 6BCX 6SB0 6SB2 6U62 5ES1
Enriched GO Terms of Interacting Partners?
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