RPTOR and WDR45B

RPTOR

WDR45B

Description regulatory associated protein of MTOR complex 1 WD repeat domain 45B
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Hypertension ( 30487518)
  • Mean arterial pressure ( 30487518)
  • NASH resolution in nonalcoholic steatohepatitis ( 31832568)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity ( 23563607)
  • Pulse pressure ( 29403010 30487518)
  • Systolic blood pressure ( 30487518)
Interacting Genes 30 interacting genes: BAHCC1 CBX8 CCDC40 CILK1 DCXR DUXAP9 EIF4EBP1 EIF4EBP2 IRS1 IRS2 LINC00839 MAPK1 MAPK3 MARK4 MLST8 MTOR NRBF2 PLD2 PRKAA1 PRKAA2 RAP1B RHEB RNF213 RPS6KA1 RPS6KB1 RRAGB TNRC6C USP36 WDR45B WIPI2 3 interacting genes: APP CCDC40 RPTOR
Entrez ID 57521 56270
HPRD ID 06184 15669
Ensembl ID ENSG00000141564 ENSG00000141580
Uniprot IDs Q6DKI0 Q8N122 Q5MNZ6
PDB IDs 5H64 6BCU 6BCX 6SB0 6SB2 6U62 6IYY 6KLR
Enriched GO Terms of Interacting Partners?
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