SERINC1 and CYP39A1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SERINC1	CYP39A1
Description		serine incorporator 1	cytochrome P450 family 39 subfamily A member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Enzyme Binding Protein-macromolecule Adaptor Activity	Iron Ion Binding Steroid 7-alpha-hydroxylase Activity Steroid Hydroxylase Activity Oxysterol 7-alpha-hydroxylase Activity Heme Binding 24-hydroxycholesterol 7alpha-hydroxylase Activity
	Biological Process	Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process Phospholipid Biosynthetic Process Membrane Biogenesis Positive Regulation Of CDP-diacylglycerol-serine O-phosphatidyltransferase Activity Positive Regulation Of Serine C-palmitoyltransferase Activity	Bile Acid Biosynthetic Process Cholesterol Catabolic Process Digestion Sterol Metabolic Process Cholesterol Homeostasis
Pathways		Serine biosynthesis	Synthesis of bile acids and bile salts via 24-hydroxycholesterol Endogenous sterols
Drugs
Diseases
GWAS		Plateletcrit ( 32888494 27863252)	Normal facial asymmetry (deformation magnitude) ( 30631343)
Interacting Genes		9 interacting genes: AQP9 CREB3 CYP39A1 FFAR3 GPR42 GPX8 MAK PAX8 ZMYND10	4 interacting genes: GLUL ORM2 SERINC1 SMYD3
Entrez ID		57515	51302
HPRD ID		15480	07067
Ensembl ID		ENSG00000111897	ENSG00000146233
Uniprot IDs		Q9NRX5	A0A087WTD2 B7Z786 Q9NYL5
PDB IDs
Enriched GO Terms of Interacting Partners?
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