CYP39A1 and ORM2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CYP39A1	ORM2
Description		cytochrome P450 family 39 subfamily A member 1	orosomucoid 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Azurophil Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Iron Ion Binding Steroid 7-alpha-hydroxylase Activity Steroid Hydroxylase Activity Oxysterol 7-alpha-hydroxylase Activity Heme Binding 24-hydroxycholesterol 7alpha-hydroxylase Activity
	Biological Process	Bile Acid Biosynthetic Process Cholesterol Catabolic Process Digestion Sterol Metabolic Process Cholesterol Homeostasis	Regulation Of Immune System Process Acute-phase Response Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Positive Regulation Of Tumor Necrosis Factor Production
Pathways		Synthesis of bile acids and bile salts via 24-hydroxycholesterol Endogenous sterols	Platelet degranulation Neutrophil degranulation
Drugs			Disopyramide Lidocaine Imipramine Chlorpromazine Thalidomide Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Normal facial asymmetry (deformation magnitude) ( 30631343)	Blood protein levels ( 29875488)
Interacting Genes		4 interacting genes: GLUL ORM2 SERINC1 SMYD3	4 interacting genes: BBS5 CYP39A1 PRDX6 STK3
Entrez ID		51302	5005
HPRD ID		07067	00725
Ensembl ID		ENSG00000146233	ENSG00000228278
Uniprot IDs		A0A087WTD2 B7Z786 Q9NYL5	P19652
PDB IDs			3APU 3APV 3APW 3APX
Enriched GO Terms of Interacting Partners?
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