PGLYRP4 and TRPC4AP

		PGLYRP4	TRPC4AP
Description		peptidoglycan recognition protein 4	transient receptor potential cation channel subfamily C member 4 associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Membrane Protein-containing Complex	Plasma Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Zinc Ion Binding N-acetylmuramoyl-L-alanine Amidase Activity Peptidoglycan Immune Receptor Activity Peptidoglycan Binding Protein Heterodimerization Activity	Calcium Channel Activity Protein Binding Phosphatase Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Peptidoglycan Catabolic Process Detection Of Bacterium Killing Of Cells Of Other Organism Innate Immune Response Defense Response To Gram-positive Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Hair Follicle Maturation Calcium Ion Transmembrane Transport Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways		Antimicrobial peptides	TRP channels
Drugs
Diseases
GWAS		Asthma ( 31619474)	Basal cell carcinoma ( 33549134) Blood protein levels ( 28240269) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Prothrombin time ( 22703881) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: TRPC4AP	18 interacting genes: CHMP4C CHUK CPNE1 CUL4B EDEM2 IKBKB IKBKG MED26 MTDH PCDH11X PGLYRP4 RIPK1 TAB1 TNFRSF1A TRADD TRAF2 UQCC1 VMP1
Entrez ID		57115	26133
HPRD ID		16298	09238
Ensembl ID		ENSG00000163218	ENSG00000100991
Uniprot IDs		Q96LB8	B4DW48 Q8TEL6
PDB IDs		2EAV 2EAX
Enriched GO Terms of Interacting Partners?
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