CYSLTR2 and ATP5MC2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CYSLTR2	ATP5MC2
Description		cysteinyl leukotriene receptor 2	ATP synthase membrane subunit c locus 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Plasma Membrane Integral Component Of Plasma Membrane	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrial Outer Membrane Integral Component Of Membrane Proton-transporting ATP Synthase Complex, Coupling Factor F(o)
	Molecular Function	Cysteinyl Leukotriene Receptor Activity Leukotriene Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding G Protein-coupled Peptide Receptor Activity	Protein Binding Lipid Binding Proton Transmembrane Transporter Activity
	Biological Process	Immune Response Neuropeptide Signaling Pathway Regulation Of Catalytic Activity Leukotriene Signaling Pathway Cellular Response To Glucagon Stimulus	ATP Synthesis Coupled Proton Transport
Pathways		Glucagon signaling in metabolic regulation Leukotriene receptors G alpha (q) signalling events G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production LTC4-CYSLTR mediated IL4 production	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs		Nedocromil Leukotriene C4 Leukotriene D4
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		19 interacting genes: ATP5MC2 DBI ENO1 GNAS GRIK1 HSP90B1 KRTAP1-1 LNX1 MTUS2 NCKIPSD PCDH9 PCMT1 RNASEK RNF144A RTN4 SVOP TTC19 YIPF6 YWHAE	4 interacting genes: ATP13A2 CYSLTR2 TDP2 XRN1
Entrez ID		57105	517
HPRD ID		09293	04429
Ensembl ID		ENSG00000152207	ENSG00000135390
Uniprot IDs		A4ZKH2 Q5KU17 Q9NS75	Q06055
PDB IDs
Enriched GO Terms of Interacting Partners?
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