CYSLTR2 and DBI

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CYSLTR2	DBI
Description		cysteinyl leukotriene receptor 2	diazepam binding inhibitor, acyl-CoA binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Plasma Membrane Integral Component Of Plasma Membrane	Endoplasmic Reticulum Lumen Golgi Apparatus Protein-lipid Complex Extracellular Exosome
	Molecular Function	Cysteinyl Leukotriene Receptor Activity Leukotriene Receptor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding G Protein-coupled Peptide Receptor Activity	Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Identical Protein Binding
	Biological Process	Immune Response Neuropeptide Signaling Pathway Regulation Of Catalytic Activity Leukotriene Signaling Pathway Cellular Response To Glucagon Stimulus	Phosphatidylcholine Acyl-chain Remodeling Negative Regulation Of Protein Lipidation Positive Regulation Of CoA-transferase Activity Positive Regulation Of Phospholipid Transport
Pathways		Glucagon signaling in metabolic regulation Leukotriene receptors G alpha (q) signalling events G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production LTC4-CYSLTR mediated IL4 production	Mitochondrial Fatty Acid Beta-Oxidation
Drugs		Nedocromil Leukotriene C4 Leukotriene D4	Coenzyme A Hexadecanal
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Systemic juvenile idiopathic arthritis ( 27927641)	Obesity-related traits ( 23251661)
Interacting Genes		19 interacting genes: ATP5MC2 DBI ENO1 GNAS GRIK1 HSP90B1 KRTAP1-1 LNX1 MTUS2 NCKIPSD PCDH9 PCMT1 RNASEK RNF144A RTN4 SVOP TTC19 YIPF6 YWHAE	14 interacting genes: CYSLTR2 DDIT4L DUSP23 GSK3B LAMTOR5 MAP1LC3B NIPSNAP1 NSFL1C PFDN2 PPCDC RAD23A RAD23B TSPO UBXN2A
Entrez ID		57105	1622
HPRD ID		09293	08832
Ensembl ID		ENSG00000152207	ENSG00000155368
Uniprot IDs		A4ZKH2 Q5KU17 Q9NS75	A0A024RAF2 B8ZWD1 B8ZWD8 P07108
PDB IDs			2CB8 2FJ9
Enriched GO Terms of Interacting Partners?
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