PRTFDC1 and GNPDA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		PRTFDC1	GNPDA1
Description		phosphoribosyl transferase domain containing 1	glucosamine-6-phosphate deaminase 1
Image
GO Annotations	Cellular Component		Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity	Glucosamine-6-phosphate Deaminase Activity Protein Binding Identical Protein Binding
	Biological Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process Generation Of Precursor Metabolites And Energy Single Fertilization N-acetylneuraminate Catabolic Process
Pathways			Glycolysis
Drugs			Beta-D-Glucose 2-Deoxy-2-Amino Glucitol-6-Phosphate N-acetyl-D-glucosamine-6-phosphate
Diseases
GWAS		Body shape index ( 34021172) Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 32888494 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Asthma ( 31959851 29273806) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Mean platelet volume ( 32888494) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		21 interacting genes: - CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 GPR158 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 RAB18 SPG21 STAT5A TCL1A TMEM14B VWA5A	5 interacting genes: EWSR1 HSP90AB1 MAGEA11 PRTFDC1 STK11
Entrez ID		56952	10007
HPRD ID		17917	09048
Ensembl ID		ENSG00000099256	ENSG00000113552
Uniprot IDs		Q9NRG1	P46926
PDB IDs		2JBH	1NE7
Enriched GO Terms of Interacting Partners?
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