GNPDA1 and PRTFDC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		GNPDA1	PRTFDC1
Description		glucosamine-6-phosphate deaminase 1	phosphoribosyl transferase domain containing 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Glucosamine-6-phosphate Deaminase Activity Protein Binding Identical Protein Binding	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Carbohydrate Metabolic Process Glucosamine Catabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process Generation Of Precursor Metabolites And Energy Single Fertilization N-acetylneuraminate Catabolic Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process
Pathways		Glycolysis
Drugs		Beta-D-Glucose 2-Deoxy-2-Amino Glucitol-6-Phosphate N-acetyl-D-glucosamine-6-phosphate
Diseases
GWAS		Asthma ( 31959851 29273806) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Mean platelet volume ( 32888494) Squamous cell lung carcinoma ( 28604730)	Body shape index ( 34021172) Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 32888494 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		5 interacting genes: EWSR1 HSP90AB1 MAGEA11 PRTFDC1 STK11	21 interacting genes: - CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 GPR158 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 RAB18 SPG21 STAT5A TCL1A TMEM14B VWA5A
Entrez ID		10007	56952
HPRD ID		09048	17917
Ensembl ID		ENSG00000113552	ENSG00000099256
Uniprot IDs		P46926	Q9NRG1
PDB IDs		1NE7	2JBH
Enriched GO Terms of Interacting Partners?
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