C1GALT1 and TMEM52B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C1GALT1	TMEM52B
Description		core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	transmembrane protein 52B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Activity Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	Angiogenesis Kidney Development O-glycan Processing, Core 1 Cell Differentiation	Biological_process
Pathways		Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 30224653) Erosive tooth wear (severe vs non-severe) ( 29898447) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Multiple sclerosis (severity) ( 19010793) Night sleep phenotypes ( 27126917) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Serum galactose-deficient IgA1 levels ( 28187132) Serum galactose-deficient IgA1 levels in IgA nephropathy ( 33593824) Smooth-surface caries ( 24556642) Systolic blood pressure ( 26969751) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		32 interacting genes: ANKS6 ARL13B C1GALT1C1 CD79A CPLX4 ELOVL4 FAM209A FAM210B GJA8 GJB1 GJB5 GPR101 GPR151 GPR42 GPRC5D GPX8 GSDME LEPROT LEUTX LHFPL5 MUC1 PIGP RETREG3 SLC14A1 SLC1A1 SLC7A14 STX1A TMEM14B TMEM237 TMEM52B TRAF6 XRN1	68 interacting genes: ALG3 APOD APOL2 APOL3 BET1 BTN2A2 C1GALT1 C3orf52 CLDN19 CLDN4 CNIH1 CNIH3 CSGALNACT2 DNAJC30 EMD FXYD3 GAST GPR25 GPR37L1 IGFBP5 INSIG2 ITGAM JAGN1 LHFPL5 LPAR3 LTC4S MAL MARCHF2 MIP MS4A13 NINJ2 NRM NSG1 ORMDL1 PEDS1-UBE2V1 PGAP2 PLN PLP1 RTP2 SEC22A SERP1 SLC30A2 SLC30A8 SLC35A4 SLC35B4 SLC38A7 SMIM1 TF TMEM100 TMEM107 TMEM109 TMEM128 TMEM147 TMEM14C TMEM203 TMEM218 TMEM267 TMEM50B TMEM54 TMEM60 TMEM86B TMEM97 TMUB2 TRAM1L1 TRARG1 VAMP3 VAMP5 ZDHHC15
Entrez ID		56913	120939
HPRD ID		16631	08709
Ensembl ID		ENSG00000106392	ENSG00000165685
Uniprot IDs		A0A024RA32 Q9NS00	Q4KMG9
PDB IDs
Enriched GO Terms of Interacting Partners?
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