TMPRSS4 and BNIP3L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMPRSS4	BNIP3L
Description		transmembrane serine protease 4	BCL2 interacting protein 3 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane Secretory Granule	Nucleus Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Nuclear Speck Intrinsic Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Proteolysis Endocytosis Response To Wounding Regulation Of Gene Expression Protein Processing Negative Regulation Of Growth Rate Positive Regulation Of Viral Entry Into Host Cell	Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Defense Response To Virus Negative Regulation Of Cell Death Cellular Response To Hypoxia Mitochondrial Outer Membrane Permeabilization Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion
Pathways			TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252) Schizophrenia ( 28991256 30285260)
Interacting Genes		15 interacting genes: BNIP3L CLEC7A CLRN1 ERVFRD-1 FAM209A FNDC9 GPX8 KASH5 LMNA NLRX1 RASGRP4 SIGLEC12 SUSD3 SYNE4 TMEM79	35 interacting genes: ADIPOQ BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 CYB5B DOK5 DUSP3 ECM1 EWSR1 FATE1 GABARAPL1 GABARAPL2 GBP2 GNB5 HTR2B KEAP1 KLHL23 LDLRAD1 LMNA MALL MAP1LC3A NGFR RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11 TMEM120B TMPRSS4 TNMD
Entrez ID		56649	665
HPRD ID		05952	07288
Ensembl ID		ENSG00000137648	ENSG00000104765
Uniprot IDs		B7Z458 B7Z8X1 B7Z900 Q9NRS4	O60238 Q6IBV1
PDB IDs
Enriched GO Terms of Interacting Partners?
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