LTB4R2 and SLC2A1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		LTB4R2	SLC2A1
Description		leukotriene B4 receptor 2	solute carrier family 2 member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane	Golgi Membrane Photoreceptor Inner Segment Female Pronucleus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Caveola Intercalated Disc Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Z Disc Midbody Cortical Actin Cytoskeleton Sarcolemma Melanosome Extracellular Exosome Blood Microparticle Presynapse
	Molecular Function	Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity	Long-chain Fatty Acid Transporter Activity Glucose Transmembrane Transporter Activity Protein Binding Kinase Binding Dehydroascorbic Acid Transmembrane Transporter Activity Identical Protein Binding Xenobiotic Transmembrane Transporter Activity Protein Self-association D-glucose Transmembrane Transporter Activity
	Biological Process	Chemotaxis Inflammatory Response Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway	Response To Hypoxia Central Nervous System Development Female Pregnancy Long-chain Fatty Acid Import Across Plasma Membrane L-ascorbic Acid Metabolic Process Cerebral Cortex Development Response To Insulin Cellular Response To Glucose Starvation Xenobiotic Transport Photoreceptor Cell Maintenance Protein-containing Complex Assembly Dehydroascorbic Acid Transport Cellular Response To Mechanical Stimulus Cellular Hyperosmotic Response Glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier Response To Thyroglobulin Triiodothyronine Glucose Transmembrane Transport
Pathways		Leukotriene receptors G alpha (q) signalling events	Cellular hexose transport Vitamin C (ascorbate) metabolism Regulation of insulin secretion Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) Lactose synthesis
Drugs		Amelubant Leukotriene B4	Resveratrol Carboxymethylcellulose
Diseases
GWAS		Anorectal malformation ( 31136621) Height ( 28552196)	Birth weight ( 31043758) Cardiac hypertrophy ( 21348951) Immature fraction of reticulocytes ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Pre-treatment viral load in HIV-1 infection ( 31219150) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) White blood cell count ( 32888494)
Interacting Genes		48 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MUC1 MYO1E OBSL1 P4HTM PER1 PIGM PKD1 PTGIS RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B	24 interacting genes: ADNP BMP8B CALR CANX CCR2 CDKN1C CHRNB4 COPS6 FAAH GAPDH GCN1 GIPC1 GPR35 HSPB2 LTB4R2 PDIA3 PTK2B PTPRU SMAP2 STOM SUMO1 UBE2I VHL ZRSR2
Entrez ID		56413	6513
HPRD ID		16153	00683
Ensembl ID		ENSG00000213906	ENSG00000117394
Uniprot IDs		B4E292 Q9NPC1	P11166 Q59GX2
PDB IDs			1SUK 4PYP 5EQG 5EQH 5EQI 6THA
Enriched GO Terms of Interacting Partners?
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