PRRG2 and WWTR1

Number of citations of the paper that reports this interaction (PubMedID 23873930)
7

Data Source:
BioGRID (pull down)

		PRRG2	WWTR1
Description		proline rich and Gla domain 2	WW domain containing transcription regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane	Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Nuclear Body
	Molecular Function	Calcium Ion Binding Protein Binding	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Homodimerization Activity
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Tissue Homeostasis Negative Regulation Of Protein Phosphorylation Heart Process Regulation Of Transcription, DNA-templated Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Stem Cell Division SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Glomerulus Development Multicellular Organism Growth Hippo Signaling Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Mesenchymal Cell Differentiation Cilium Assembly Regulation Of SMAD Protein Signal Transduction Kidney Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Localization To Nucleus
Pathways			Signaling by Hippo YAP1- and WWTR1 (TAZ)-stimulated gene expression YAP1- and WWTR1 (TAZ)-stimulated gene expression SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Physiological factors RUNX2 regulates osteoblast differentiation RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Iron status biomarkers (total iron binding capacity) ( 33536631) Red blood cell count ( 32888494 27863252) Schizophrenia ( 25056061 29483656 30285260)	Height ( 31562340) Polycystic ovary syndrome ( 32289280) Preeclampsia ( 23551011) Triglyceride levels ( 34074324)
Interacting Genes		14 interacting genes: CCL4 CRK CYTH2 FAM221A FATE1 NEDD4 NEDD4L NKG7 PPP2R1A RTN4RL1 SGTA SNX15 WWTR1 YAP1	26 interacting genes: C1orf74 DAPK1 IL16 LATS1 LATS2 MFHAS1 NKX2-1 PAX3 PLOD2 PPP1CA PRRG2 PRRG4 RTN4IP1 RUNX1 SLC9A3R2 SUMO3 TCP11L1 TEAD1 TEAD2 TEAD3 TEAD4 USP10 WBP2 YWHAE YWHAG YWHAZ
Entrez ID		5639	25937
HPRD ID		09189	09580
Ensembl ID		ENSG00000126460	ENSG00000018408
Uniprot IDs		O14669	Q9GZV5
PDB IDs			5N5R 5N5T 5N5W 5N75 6RHC 6RJL 6RJQ 6RP6 6SLW 6SLX
Enriched GO Terms of Interacting Partners?
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