PRNP and APOE

  • Number of citations of the paper that reports this interaction (PubMedID 15146195)
  • 60
  • Data Source:
  • HPRD (in vivo)

PRNP

APOE

Description prion protein apolipoprotein E
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Creutzfeldt-Jakob disease ( 19081515)
  • Creutzfeldt-Jakob disease (sporadic) ( 32949544 25918841)
  • Creutzfeldt-Jakob disease (variant) ( 22137330)
  • KANNO antigen negativity ( 31020675)
  • Platelet aggregation ( 20526338)
  • Prion diseases ( 22210626)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 97 interacting genes: ABT1 ADAM23 ADAP2 ADRB2 AGO1 AIFM3 APBB1 APLP1 APLP2 APOE ARHGAP15 ATIC BAG6 BAZ2B BRD2 C7orf50 CAV1 CCDC149 CCR1 CIRBP CLSTN1 CLU CNP CNTN1 CRYAB CSN3 CSNK2A1 CSNK2A2 CSNK2B CWC15 DDX47 DNM1 DOCK7 DPP6 DYRK3 ERI3 F2RL1 FAM27E3 FBLN5 FBXO45 FGF13 FHL1 FZD7 GRB2 HAX1 HSPA5 HSPD1 IER3 KIAA1191 KIFAP3 L1CAM LMNA LSAMP MAG MARK4 MMADHC MOG MTG1 NCAM1 NCAM2 NECTIN1 NHP2 NIPSNAP2 NOB1 OPCML P4HB PDE4DIP PLG PPFIBP2 PPP1R14A PSMA3 PSMB5 PTAFR PTRH1 PYM1 RBM22 RNPC3 RPL41 SCNM1 SEC31A SPARCL1 STARD5 STIP1 SURF2 TBPL1 TMEM237 TRIM15 TSC22D4 TSLP TYMSOS UTP4 WDR5 WDR61 ZFYVE28 ZKSCAN8 ZNF408 ZNF740 65 interacting genes: A2M ALB ANKH APOC2 APOC4 APP ARFGAP1 CD1D CD79A CDC37 CEACAM1 CNTF CSNK2A1 CST1 CTSB CYP2C18 CYP2C8 ECSIT ELAVL1 EPN2 FARSA FBXL12 FOXG1 FXYD7 GCDH HSP90AA1 HTRA1 IFIT3 IFIT5 IQSEC1 LCAT LDLR LINC02582 LONP1 LOXL4 LRP1 LRP2 LRP8 MAP2 MAPT MAST1 MID1IP1 NEFM NOS3 PCMT1 PDCD4 PLEKHA6 PLTP PRAM1 PRDX2 PRNP PSEN1 RHEB RNF32 RPL4 SCARB1 SNCA SORL1 ST13 TIMM29 TREM2 TYRO3 VLDLR ZBP1 ZNF558
Entrez ID 5621 348
HPRD ID 01453 00135
Ensembl ID ENSG00000171867 ENSG00000130203
Uniprot IDs F7VJQ1 P04156 Q53YK7 A0A0S2Z3D5 P02649
PDB IDs 1E1G 1E1J 1E1P 1E1S 1E1U 1E1W 1FKC 1FO7 1H0L 1HJM 1HJN 1I4M 1OEH 1OEI 1QLX 1QLZ 1QM0 1QM1 1QM2 1QM3 2IV4 2IV5 2IV6 2K1D 2KUN 2LBG 2LEJ 2LFT 2LSB 2LV1 2M8T 2OL9 2W9E 3HAF 3HAK 3HEQ 3HER 3HES 3HJ5 3HJX 3MD4 3MD5 3NHC 3NHD 3NVF 4DGI 4E1H 4E1I 4KML 4N9O 5L6R 5YJ4 5YJ5 6DU9 6LNI 6PQ5 6PQA 6SUZ 6SV2 6UUR 1B68 1BZ4 1EA8 1GS9 1H7I 1LE2 1LE4 1LPE 1NFN 1NFO 1OEF 1OEG 1OR2 1OR3 2KC3 2KNY 2L7B 6IWB 6NCN 6NCO
Enriched GO Terms of Interacting Partners?
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