MAPK6 and HIP1

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 136
  • Data Source:
  • BioGRID (two hybrid)

MAPK6

HIP1

Description mitogen-activated protein kinase 6 huntingtin interacting protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Frailty index ( 34431594)
  • Serum uric acid levels in response to allopurinol in gout ( 25676789)
  • Age-related nuclear cataracts ( 24951543)
  • Alcoholism (12-month weekly alcohol consumption) ( 21529783)
  • Basophil count ( 32888494)
  • Basophil percentage of granulocytes ( 27863252)
  • Basophil percentage of white cells ( 32888494 27863252)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • Body mass index ( 26961502 28892062 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Body mass index in physically active individuals ( 28448500)
  • Fasting insulin ( 33402679)
  • Interleukin-6 levels ( 22205395)
  • Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
  • Systemic lupus erythematosus ( 26663301)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 167 interacting genes: ACTG1 ACTR1B AMPH ANAPC5 ANK3 ANKRD2 APBA2 ARHGDIA ARPC3 ATG9A ATP5PF BAG6 BARX1 BBS10 CA1 CA12 CALR CASP6 CCND3 CCT3 CDH13 CERS1 CFAP298 CFL1 CNTN1 CNTRL COPS6 CSE1L CYRIB CYTH2 DBN1 DCTN2 DDOST DDR1 DGKZ DKC1 DNAJC28 DPPA4 DST DYNC2I2 EDF1 EEF1A2 EIF1 EIF3C EIF4A1 ELOF1 EMD FBXL16 FOXO3 FXYD3 GALNT7 GATA1 GLRX3 GORASP1 GPX1 HACL1 HAUS2 HDAC11 HIP1 HNRNPA0 HNRNPD HNRNPH3 HSP90AB1 HSP90B1 HSPD1 IDH3B INS ITGB3BP ITSN1 JUNB KDSR KLC1 KNSTRN LPXN MAP3K12 MAP3K7 MAPKAPK5 MASP1 MBIP MBOAT7 MCM3 MDK METTL17 METTL2A MGAT1 MIPEP MOK MON1A MTG2 MYBL2 MYOZ3 MZB1 NAT9 NAXE NDUFS6 NECTIN2 NELFB NOL4 NRXN2 NUDT5 OSTF1 PDCD6IP PDLIM1 PHACTR3 PHC2 PHGDH PIH1D1 PLEKHM1 PLSCR1 PPBP PPP1R7 PPP2R1A PRKAB1 PRKAR1A PRKCB PRPF38A PSAT1 PSIP1 PTPMT1 RAB2A RAB31 RACK1 RANBP9 RAP1GAP RARA RBL1 RGS19 RPL10 RRP7A SEPTIN3 SEPTIN5 SERPINA4 SHC1 SLC20A1 SLC41A3 SMAD6 SMS SNAPC4 SNW1 SOCS3 SPG7 SPRR2D SPTAN1 SRSF5 STX7 TCF12 TDP2 THAP4 TPI1 TTK TUBA1A UBA52 UBE2L3 URB1 USP20 VPS26C WDR26 WFS1 WWC1 XPO1 ZNF133 ZNF205 ZNF331 ZNF579 ZNF600 ZNF671 ZNF775 37 interacting genes: AP2A1 AP2B1 APAF1 CASP3 CASP8 CASP9 CFAP53 CLTA CLTB CLTC CYRIB DAZAP2 DVL2 EHHADH EIF6 FAM168A FBXO25 GLS2 HIP1R HTT IFT57 ITSN1 LITAF LNX1 MAP3K1 MAPK6 NECAP1 PFDN1 RAD23B REL RPRM RPS10 SMURF1 SYT17 TCEA2 TCEANC TFAP2A
Entrez ID 5597 3092
HPRD ID 04213 03461
Ensembl ID ENSG00000069956 ENSG00000127946
Uniprot IDs Q16659 B4DK46 O00291
PDB IDs 6YKY 6YLC 6YLL 7AQB 2NO2 2QA7 3I00
Enriched GO Terms of Interacting Partners?
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