HIP1 and APAF1

  • Number of citations of the paper that reports this interaction (PubMedID 16979168)
  • 7
  • Data Source:
  • HPRD (in vivo, in vitro)

HIP1

APAF1

Description huntingtin interacting protein 1 apoptotic peptidase activating factor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related nuclear cataracts ( 24951543)
  • Alcoholism (12-month weekly alcohol consumption) ( 21529783)
  • Basophil count ( 32888494)
  • Basophil percentage of granulocytes ( 27863252)
  • Basophil percentage of white cells ( 32888494 27863252)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • Body mass index ( 26961502 28892062 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Body mass index in physically active individuals ( 28448500)
  • Fasting insulin ( 33402679)
  • Interleukin-6 levels ( 22205395)
  • Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
  • Systemic lupus erythematosus ( 26663301)
  • White blood cell count (basophil) ( 27863252)
Interacting Genes 37 interacting genes: AP2A1 AP2B1 APAF1 CASP3 CASP8 CASP9 CFAP53 CLTA CLTB CLTC CYRIB DAZAP2 DVL2 EHHADH EIF6 FAM168A FBXO25 GLS2 HIP1R HTT IFT57 ITSN1 LITAF LNX1 MAP3K1 MAPK6 NECAP1 PFDN1 RAD23B REL RPRM RPS10 SMURF1 SYT17 TCEA2 TCEANC TFAP2A 30 interacting genes: ACADS APIP AVEN BCL2L1 BCL2L10 CASP3 CASP4 CASP8 CASP9 CCL13 CDK17 CYCS DZIP1 ELK3 FAS FEM1B HIP1 HNF1A HSP90AA1 HSPA1A MRPL19 NLRP1 NR1H4 NUDT4 PAH PPP1CA RPL26L1 TOP1 TRIAP1 UTP20
Entrez ID 3092 317
HPRD ID 03461 03755
Ensembl ID ENSG00000127946 ENSG00000120868
Uniprot IDs B4DK46 O00291 O14727
PDB IDs 2NO2 2QA7 3I00 1C15 1CWW 1CY5 1Z6T 2P1H 2YGS 3J2T 3JBT 3YGS 4RHW 5JUY 5WVC 5WVE
Enriched GO Terms of Interacting Partners?
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