DOCK10 and CCDC102B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DOCK10	CCDC102B
Description		dedicator of cytokinesis 10	coiled-coil domain containing 102B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Dendritic Spine Extracellular Exosome
	Molecular Function	Molecular_function Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	B Cell Homeostasis Marginal Zone B Cell Differentiation Small GTPase Mediated Signal Transduction Regulation Of Cell Migration Positive Regulation Of GTPase Activity Dendritic Spine Morphogenesis
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) IgE levels in asthmatics (D.p. specific) ( 23967269) LDL cholesterol levels in HIV infection ( 33109212) Mean platelet volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494) Response to bupropion and depression ( 27622933) Response to exercise (triglyceride level interaction) ( 26491034) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Triglyceride levels in HIV infection ( 33109212)	Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)
Interacting Genes		4 interacting genes: CCDC102B LURAP1 MAGEA11 RHOJ	102 interacting genes: ABI2 AK8 ANKRD23 ARL4A ARL4D BYSL C20orf202 CACNB4 CAPN3 CCDC120 CCDC187 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 CWF19L2 DISC1 DOCK10 EFHC2 EHHADH ENKD1 EXOC5 FAM161A FAM217B FBF1 FH FLOT1 FNDC11 GEM GOPC HMG20B IKZF3 KIFC3 KPNA3 KRT75 KRTAP13-3 LENG1 LMO4 LNX1 LZTS1 MAB21L2 MAGOHB MARK1 MCM7 MEOX1 MEOX2 MFAP1 MOS MSX2 NIF3L1 NME4 NTAQ1 NXT2 PFKFB4 PHAF1 PICK1 PNMA5 POMC POP5 PPP1R13B PPP1R18 PRPF18 PSMA1 RASAL3 RCOR3 RSPH14 RTL8A RTL8B RTL8C SDCBP SFN SGF29 SH3RF2 SLIRP SMARCD1 SNAPIN SORBS3 SPATA18 SPATA2 SPG21 SYCE1 SYT17 TCEANC TCP10L TFIP11 TNNI1 TPM3 TRIM27 TRIM54 TSGA10IP TTC23 VPS52 ZBTB32 ZBTB42 ZC2HC1C ZNF20 ZNF250 ZNF572 ZNF620 ZNF688 ZNF774
Entrez ID		55619	79839
HPRD ID		10919	08038
Ensembl ID		ENSG00000135905	ENSG00000150636
Uniprot IDs		Q96BY6	Q68D86
PDB IDs		6TKY 6TKZ 6TM1
Enriched GO Terms of Interacting Partners?
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