DOCK10

Description		dedicator of cytokinesis 10
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Dendritic Spine Extracellular Exosome
	Molecular Function	Molecular_function Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	B Cell Homeostasis Marginal Zone B Cell Differentiation Small GTPase Mediated Signal Transduction Regulation Of Cell Migration Positive Regulation Of GTPase Activity Dendritic Spine Morphogenesis
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) IgE levels in asthmatics (D.p. specific) ( 23967269) LDL cholesterol levels in HIV infection ( 33109212) Mean platelet volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494) Response to bupropion and depression ( 27622933) Response to exercise (triglyceride level interaction) ( 26491034) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		4 interacting genes: CCDC102B LURAP1 MAGEA11 RHOJ
Entrez ID		55619
HPRD ID		10919
Ensembl ID		ENSG00000135905
Uniprot IDs		Q96BY6
PDB IDs		6TKY 6TKZ 6TM1
Enriched GO Terms of Interacting Partners?
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