SYNJ2BP and THEM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SYNJ2BP	THEM5
Description		synaptojanin 2 binding protein	thioesterase superfamily member 5
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GO Annotations	Cellular Component	Mitochondrion Basolateral Plasma Membrane Cell Junction Integral Component Of Mitochondrial Outer Membrane Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane	Mitochondrial Matrix
	Molecular Function	Protein Binding	Protein Binding Palmitoyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis	Fatty Acid Metabolic Process Long-chain Fatty-acyl-CoA Metabolic Process Cardiolipin Acyl-chain Remodeling
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Motor coordination ( 34177493) Normal facial asymmetry (angle of surface orientation score) ( 30631343)	Asthma ( 31619474) Birth weight ( 31043758) Serum metabolite levels ( 33031748) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		34 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SMOC1 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1	2 interacting genes: MAGEA11 SYNJ2BP
Entrez ID		55333	284486
HPRD ID		15455	08233
Ensembl ID		ENSG00000213463	ENSG00000196407
Uniprot IDs		A0A024R670 P57105	Q8N1Q8
PDB IDs		2ENO 2JIK 2JIN	4AE7
Enriched GO Terms of Interacting Partners?
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