THEM5 and SYNJ2BP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		THEM5	SYNJ2BP
Description		thioesterase superfamily member 5	synaptojanin 2 binding protein
Image
GO Annotations	Cellular Component	Mitochondrial Matrix	Mitochondrion Basolateral Plasma Membrane Cell Junction Integral Component Of Mitochondrial Outer Membrane Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane
	Molecular Function	Protein Binding Palmitoyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity	Protein Binding
	Biological Process	Fatty Acid Metabolic Process Long-chain Fatty-acyl-CoA Metabolic Process Cardiolipin Acyl-chain Remodeling	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis
Pathways		Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Asthma ( 31619474) Birth weight ( 31043758) Serum metabolite levels ( 33031748) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Motor coordination ( 34177493) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		2 interacting genes: MAGEA11 SYNJ2BP	34 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SMOC1 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1
Entrez ID		284486	55333
HPRD ID		08233	15455
Ensembl ID		ENSG00000196407	ENSG00000213463
Uniprot IDs		Q8N1Q8	A0A024R670 P57105
PDB IDs		4AE7	2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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