BRIX1 and UBA2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

		BRIX1	UBA2
Description		biogenesis of ribosomes BRX1	ubiquitin like modifier activating enzyme 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome Nucleolus	Nucleoplasm Cytoplasm SUMO Activating Enzyme Complex
	Molecular Function	RNA Binding Protein Binding RRNA Binding	Magnesium Ion Binding Protein Binding ATP Binding Transferase Activity SUMO Activating Enzyme Activity SUMO Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein Heterodimerization Activity
	Biological Process	Ribosomal Large Subunit Assembly RRNA Processing	Protein Sumoylation Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Sumoylation
Pathways			SUMO is conjugated to E1 (UBA2:SAE1) SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: CD48 EBNA1BP2 GSK3B SETDB1 UBA2 UNC119	17 interacting genes: BRIX1 CHEK1 ERCC6 ETV4 MEOX2 NEDD8 PARK7 RAD23B SAE1 SERBP1 SUMO1 SUMO1P1 SUMO2 SUMO3 UBC UBD UBE2I
Entrez ID		55299	10054
HPRD ID		16563	11658
Ensembl ID		ENSG00000113460	ENSG00000126261
Uniprot IDs		Q8TDN6	Q9UBT2
PDB IDs			1Y8Q 1Y8R 2PX9 3KYC 3KYD 4W5V 5FQ2 6CWY 6CWZ
Enriched GO Terms of Interacting Partners?
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