UBA2 and RAD23B

Number of citations of the paper that reports this interaction (PubMedID 22863883)
127

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		UBA2	RAD23B
Description		ubiquitin like modifier activating enzyme 2	RAD23 homolog B, nucleotide excision repair protein
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm SUMO Activating Enzyme Complex	Proteasome Complex Nucleus Nucleoplasm Cytosol XPC Complex
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Transferase Activity SUMO Activating Enzyme Activity SUMO Binding Small Protein Activating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein Heterodimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding
	Biological Process	Protein Sumoylation Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Sumoylation	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair Spermatogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Cellular Response To Interleukin-7
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9)	N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS			Body mass index ( 20966902) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)
Interacting Genes		17 interacting genes: BRIX1 CHEK1 ERCC6 ETV4 MEOX2 NEDD8 PARK7 RAD23B SAE1 SERBP1 SUMO1 SUMO1P1 SUMO2 SUMO3 UBC UBD UBE2I	30 interacting genes: ADRM1 ATXN3 CALM1 DBI DEAF1 HIP1 HMGB1 MKRN1 MLH1 MPG NGLY1 OGT PAQR3 PAX3 PNMA5 POU6F2 PSMC2 PSMD4 PUF60 RPA1 RSC1A1 TAX1BP1 TDG UBA2 UBB UBC UBE3A USP25 XPC ZFAND5
Entrez ID		10054	5887
HPRD ID		11658	06772
Ensembl ID		ENSG00000126261	ENSG00000119318
Uniprot IDs		Q9UBT2	B7Z4W4 P54727
PDB IDs		1Y8Q 1Y8R 2PX9 3KYC 3KYD 4W5V 5FQ2 6CWY 6CWZ	1P1A 1PVE 1UEL
Enriched GO Terms of Interacting Partners?
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