TRIM68 and LZTFL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM68	LZTFL1
Description		tripartite motif containing 68	leucine zipper transcription factor like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Histone Acetyltransferase Binding Identical Protein Binding Protein Homodimerization Activity Androgen Receptor Binding Ubiquitin Protein Ligase Activity	Protein Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Regulation Of Androgen Receptor Signaling Pathway	Negative Regulation Of Protein Localization To Cilium Negative Regulation Of Protein Localization To Ciliary Membrane
Pathways		Interferon gamma signaling	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Malaria ( 31844061) Mean corpuscular hemoglobin ( 28548082) Mean corpuscular hemoglobin concentration ( 28548082) Mean corpuscular volume ( 28548082) Red blood cell count ( 28548082) White blood cell count ( 28548082)	Acne (severe) ( 24927181) COVID-19 (critical illness vs population) ( 33307546) Eosinophil percentage of white cells ( 32888494) Methadone dose in opioid dependence ( 28115739) Multiple sclerosis ( 31604244) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		14 interacting genes: DISC1 INCA1 KRTAP13-2 KRTAP13-3 LNX1 LZTFL1 NUDT16L1 POLR2G REL TCF4 TEPSIN UBE2D3 UBE2U ZBTB42	10 interacting genes: EHHADH FZD5 MOB1A NTAQ1 PELI2 PICK1 PSMA1 PSMB1 SDCBP TRIM68
Entrez ID		55128	54585
HPRD ID		11507	07586
Ensembl ID		ENSG00000167333	ENSG00000163818
Uniprot IDs		Q6AZZ1	Q9NQ48
PDB IDs
Enriched GO Terms of Interacting Partners?
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