TMEM51 and SEC61G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM51	SEC61G
Description		transmembrane protein 51	SEC61 translocon subunit gamma
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Cytosol Membrane Integral Component Of Membrane Ssh1 Translocon Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding Protein Transmembrane Transporter Activity
	Biological Process	Biological_process	Posttranslational Protein Targeting To Membrane, Translocation Protein Targeting To ER
Pathways			ER-Phagosome pathway SRP-dependent cotranslational protein targeting to membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Acute ischemic stroke x type 2 diabetes interaction ( 32541925) Cocaine use disorder ( 31490055) Cocaine use disorder x non-traditional parental care interaction ( 31490055)	Metabolite levels ( 23823483) Systemic lupus erythematosus ( 24871463) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		36 interacting genes: AQP6 BCL2L13 C14orf180 C4orf3 CCDC167 CCL4L2 CLCA4 CREB3 CYB5R3 CYP4F2 EBP GET3 LMNA MRPL12 NINJ2 PLP2 PTPN5 REEP4 RTP2 SEC61G SFT2D2 SFXN3 SMAGP SMIM1 STRIT1 TMEM107 TMEM14A TMEM14B TMEM242 TMEM254 TMIE TMX2 TSNARE1 UBE2J1 VAMP4 VTI1B	10 interacting genes: AQP6 CREB3 CREB3L1 FAM209A LCN2 LRRC25 PEX12 SEC61A1 SFTPC TMEM51
Entrez ID		55092	23480
HPRD ID		07651	15318
Ensembl ID		ENSG00000171729	ENSG00000132432
Uniprot IDs		A0A024QZ97 Q9BSA0 Q9NW97	A0A024QYZ0 P60059
PDB IDs			6W6L
Enriched GO Terms of Interacting Partners?
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