PLEKHB2 and UBC

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

PLEKHB2

UBC

Description pleckstrin homology domain containing B2 ubiquitin C
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 33339817)
  • Total cholesterol levels ( 29403010)
Interacting Genes 52 interacting genes: ATF7IP BHLHE40 C1orf94 CD68 CDA CFC1 CLDN19 DAZAP2 DCUN1D1 EMP1 EMP3 EPN1 EPN2 FAM168A FOXD4L3 GGA3 GJB2 GLIS2 GPR45 HEY1 HEYL HGS HIVEP1 MAP3K1 MED25 MTURN NRGN NTAQ1 OTUB2 PIP4P1 PITX1 POGZ PROP1 RHBDD1 RPS27A SFT2D1 SNRPB STAM2 SYNGR1 TAX1BP1 TRARG1 UBA52 UBAC1 UBAP2 UBASH3A UBB UBC UBQLN2 UBXN6 UPF1 YOD1 ZFAND2A 642 interacting genes: ABCB7 ABL1 ABRAXAS1 ABRAXAS2 ACTA1 ACTC1 ACTL8 ADH7 ADRM1 AGO2 AGRN AGTPBP1 ALG1 AMFR AMPH ANAPC1 ANAPC11 ANAPC2 ANAPC7 ANGPTL3 ANKIB1 ANKRD13A ANKRD13B ANKRD13D ANKRD30A ANKS1A ANKS1B ANP32E ANTXR1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 AREL1 ARIH1 ARIH2 ARMC1 ARRB2 ASB11 ASB2 ASCC2 ASCC3 ASXL1 ASXL2 ATP5PD ATXN3 ATXN3L ATXN7L3 B3GALT1 BABAM1 BABAM2 BAP1 BARD1 BARX1 BCAS2 BCR BECN1 BFAR BIN1 BIRC2 BIRC3 BRAP BRCA1 BRCC3 BRF1 BSG BTD BTRC C8orf34 CAPN15 CASP8 CAVIN1 CAVIN3 CBL CBLB CBLC CBR1 CBR3 CCDC50 CCDC92 CD2 CD2AP CDC20 CDC42 CDC45 CDH2 CDH22 CDIP1 CDK17 CDY1B CENPE CEP164 CEP192 CEP55 CEP83 CFAP36 CHD3 CHGA CHP1 CHUK CLN8 CLU COL1A1 COPB1 CPT1A CRACD CTBP2 CTRC CUEDC1 CUEDC2 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYLD DAXX DAZAP2 DCUN1D1 DDI1 DDI2 DDX19B DDX58 DECR2 DENR DESI1 DHX15 DLGAP4 DMBX1 DNAH7 DNAJB2 DNASE2B DOCK6 DPH1 DPY30 ECE2 EFS EIF3A EIF3H ELL ELOVL5 EP300 EPN1 EPN2 EPN3 EPS15 EPS15L1 ERCC6 ERGIC2 ERVK13-1 EXOSC8 FAAP20 FAF1 FAM168A FAN1 FAT1 FBH1 FBXL15 FBXO44 FCHO2 FETUB FGA FIS1 FLOT1 FLOT2 FSHR GARNL3 GBF1 GFPT2 GFUS GGA1 GGA3 GLG1 GRB2 GTF2H1 GTF2I GTF2IRD1 H2AC18 H2AC20 H2BC21 HACD1 HACD2 HAVCR1 HDAC5 HDAC6 HECW1 HERC1 HERC2 HERC3 HERC4 HGS HLTF HMGB1 HMGN2 HNRNPM HPDL HRNR HSD17B11 HSPA8 HSPG2 HUWE1 HYDIN HYDIN2 IDE IGF1R IKBKB IKBKG ILF3 ING1 INPPL1 IRS1 ISX ITCH ITGAV ITSN2 JOSD1 JOSD2 JUN KCTD7 KDM3B KEAP1 KEL KHDRBS1 KIAA0586 KLHL11 KLHL13 KLHL7 LACTB LAMA1 LAMA5 LAMB1 LAMC1 LAPTM5 LARP1B LIMA1 LINC02593 LNPK LTF LTN1 MACF1 MAD1L1 MALT1 MAP2K4 MAP3K7 MAP4 MAPRE2 MARCHF6 MARCHF7 MBOAT7 MDM2 MDM4 MDN1 MED15 MINDY1 MINDY2 MINDY3 MINDY4 MORC3 MRPL37 MTERF4 MTURN MUC16 MUC5B MUL1 MVP MYCBP MYL1 MYL3 MYO6 NAA10 NAT10 NBPF1 NBPF10 NBPF11 NBPF12 NBPF14 NBPF8 NBPF9 NBR1 NCK2 NCKAP5L NCOA6 NDC1 NDUFB9 NDUFS8 NEDD4 NEDD4L NEK8 NEURL3 NFIA NFX1 NPLOC4 NPM1 NPTN NSFL1C NSMCE1 NT5C1B NXPH4 OGT OPA3 OPRM1 OR7G3 OSBPL8 OTOG OTUB1 OTUB2 OTUD1 OTUD3 OTUD4 OTUD5 OTUD6A OTUD6B OTUD7A OTUD7B P4HTM PABPC4 PARP10 PCBP2 PCMTD1 PDCD6IP PDE12 PDS5A PEDS1 PELI1 PHF20L1 PHPT1 PIK3C2B PLAA PLEC PLEKHB2 PLSCR4 PMS2 POLH POLI POLR2C POP5 PPA1 PPARG PPARGC1A PPL PPM1D PRAME PRDX4 PRKCI PRKN PRPF8 PRR23B PSMA6 PSMD10 PSMD13 PSMD4 PSMD6 PSMD7 PSMD8 PTH1R PTOV1 PTPN2 PTPN23 PUS7L R3HDM4 RABEP1 RABEP2 RABGEF1 RAC1 RAD18 RAD23A RAD23B RAG1 RASAL2 RB1CC1 RBCK1 RC3H2 RCHY1 RECQL REV1 RFC1 RGPD3 RGS2 RIOK3 RLIM RNF11 RNF111 RNF114 RNF115 RNF123 RNF125 RNF126 RNF130 RNF144A RNF144B RNF145 RNF151 RNF165 RNF168 RNF169 RNF181 RNF182 RNF2 RNF216 RNF31 RNF38 RNF4 RNF5 RNF8 RPL12 RPL7L1 RPN1 RPS3 RTL8B RTL8C RTTN RYBP SBF2 SCD SDC4 SDCBP SDF2 SDK1 SEMA3F SEPTIN1 SEPTIN7P2 SFPQ SGK1 SGPP1 SH3KBP1 SHARPIN SLC27A2 SLC38A5 SLC5A6 SLIT2 SLX4 SMAD1 SMURF1 SMURF2 SMYD4 SNCA SNRNP25 SNRPA SNTB2 SNTG1 SOCS5 SPAG1 SPECC1L SPRTN SRPRB STAM STAM2 STAMBP STAMBPL1 STUB1 STX3 SUN5 SYNE2 TAB1 TAB2 TAC3 TAPBP TAX1BP1 TBC1D15 TBC1D5 TBXAS1 TCAF1 TCEAL1 TCHH TCOF1 TCP10L3 TDRD3 THG1L TIAM1 TMEM120A TMEM132A TMEM160 TMEM201 TMEM223 TNFAIP3 TNFAIP6 TNIP1 TNIP2 TNIP3 TNRC6A TNRC6C TOLLIP TOM1 TOM1L1 TOM1L2 TOPORS TOR1AIP2 TRAF2 TRAF3IP2 TRAF5 TRAF6 TRAFD1 TRAM1 TRIM17 TRIM21 TRIM23 TRIM25 TRIM32 TRIM36 TRIM39 TRIM5 TRIP12 TRIP4 TSG101 TTC28 TTC36 TTF2 TUBA3C TUBA3D TUBGCP2 UBA1 UBA2 UBA6 UBAC1 UBAC2 UBAP1 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2G2 UBE2J1 UBE2J2 UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2V1 UBE2V2 UBE3A UBFD1 UBL7 UBQLN1 UBQLN2 UBQLN4 UBR4 UBR5 UBXN1 UBXN6 UBXN7 UCHL1 UCHL3 UCHL5 UEVLD UFD1 UIMC1 ULK1 UNC79 UNC93B3 USP1 USP10 USP11 USP12 USP13 USP14 USP16 USP17L2 USP19 USP2 USP21 USP22 USP24 USP25 USP27X USP28 USP3 USP30 USP31 USP32 USP33 USP34 USP35 USP36 USP37 USP38 USP4 USP40 USP42 USP45 USP46 USP47 USP48 USP5 USP53 USP54 USP6 USP7 USP8 USP9X USP9Y VCP VCPIP1 VPS28 VPS36 VPS37A VPS37C VPS50 WARS1 WBP2 WDR33 WDR48 WFDC8 WRNIP1 WWP1 WWP2 XIAP XPNPEP1 XRCC5 XRCC6 YAF2 YARS2 YIPF5 YOD1 YWHAB YWHAG YWHAZ ZBTB1 ZC3H12A ZCWPW2 ZFAND2B ZFAND3 ZFAND5 ZFAND6 ZFYVE9 ZHX1 ZNF148 ZNF213 ZNF451 ZNF705G ZNF716 ZNF792 ZNRF1 ZNRF2 ZRANB1 ZUP1
Entrez ID 55041 7316
HPRD ID 15144 07038
Ensembl ID ENSG00000115762 ENSG00000150991
Uniprot IDs A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7 P0CG48
PDB IDs 3AJ4 3VIA 1C3T 1CMX 1D3Z 1F9J 1FXT 1G6J 1GJZ 1NBF 1OGW 1Q5W 1S1Q 1SIF 1TBE 1UBI 1UBQ 1UD7 1XD3 1XQQ 1YX5 1YX6 1ZGU 1ZO6 2AYO 2BGF 2DEN 2FUH 2G45 2GBJ 2GBK 2GBM 2GBN 2GBR 2GMI 2HTH 2IBI 2J7Q 2JF5 2JRI 2JY6 2JZZ 2K25 2K6D 2K8B 2K8C 2KDF 2KHW 2KJH 2KLG 2KN5 2KX0 2L3Z 2LD9 2LVO 2LVP 2LVQ 2LZ6 2MBO 2MBQ 2MCN 2MI8 2MJ5 2MOR 2MRE 2MWS 2N2K 2NR2 2O6V 2OJR 2PE9 2PEA 2RR9 2RU6 2W9N 2WDT 2XEW 2Y5B 2Z59 2ZCB 2ZVN 2ZVO 3A33 3ALB 3AUL 3B08 3B0A 3BY4 3C0R 3DVG 3DVN 3EEC 3EFU 3EHV 3H7P 3H7S 3HM3 3I3T 3IFW 3IHP 3JSV 3JVZ 3JW0 3K9O 3K9P 3KVF 3KW5 3LDZ 3MHS 3MTN 3N30 3N32 3N3K 3NS8 3O65 3OFI 3OJ3 3OJ4 3ONS 3PRM 3PT2 3PTF 3Q3F 3RUL 3TMP 3U30 3UGB 3V6C 3V6E 3VFK 3VUW 3VUX 3VUY 3WXE 3WXF 3ZLZ 3ZNH 3ZNI 3ZNZ 4AP4 4AUQ 4BOS 4BOZ 4BVU 4DDG 4DDI 4DHJ 4DHZ 4FJV 4HK2 4HXD 4I6L 4I6N 4IG7 4IUM 4JQW 4K1R 4K7S 4K7U 4K7W 4KSK 4KSL 4LCD 4LDT 4MDK 4MM3 4MSM 4MSQ 4NQK 4UN2 4V3K 4V3L 4WZP 4XOK 4XOL 4ZQS 5A5B 5AF4 5AF5 5AF6 5AIT 5AIU 5B83 5C7J 5C7M 5E6J 5H07 5NL4 5NLF 5NLI 5NMC 5OE7 5OHV 5OXH 5OXI 5UDH 5WQ4 5ZQ3 5ZQ4 5ZQ5 5ZQ6 5ZQ7 6A43 6A44 6AQR 6B7M 6B7O 6EQI 6K2U 6KBE 6N13 6N6R 6NQA 6NXK 6OI4 6P5B 6Q00 6QML 6RYA 6S53 6SQR 6T7F 6T9L 6TNF 6TTU 6TUV 6TXB 6ULH 6UMP 6UMS 6UPU 6V5D 6VAE 6VAF 6VEN 6W9D 6W9R 6W9S 6WJD 6WKR 6WTG 7B5L 7B5M 7B5N 7BBD 7BBF 7BXG 7K6P 7K6Q
Enriched GO Terms of Interacting Partners?
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