UBC and TRAF2

Number of citations of the paper that reports this interaction (PubMedID 15327770)
312

Data Source:
BioGRID (enzymatic study, enzymatic study)

		UBC	TRAF2
Description		ubiquitin C	TNF receptor associated factor 2
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Endocytic Vesicle Membrane Vesicle Extracellular Exosome	Ubiquitin Ligase Complex Tumor Necrosis Factor Receptor Superfamily Complex Nucleoplasm Cytosol Cell Cortex Cytoplasmic Side Of Plasma Membrane Vesicle Membrane CD40 Receptor Complex Membrane Raft TRAF2-GSTP1 Complex Plasma Membrane Signaling Receptor Complex IRE1-TRAF2-ASK1 Complex
	Molecular Function	Protease Binding RNA Binding Protein Binding Protein Tag Ubiquitin Protein Ligase Binding	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding CD40 Receptor Binding Protein Binding Zinc Ion Binding Enzyme Binding Protein Kinase Binding Protein Phosphatase Binding Protein-macromolecule Adaptor Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding Tumor Necrosis Factor Binding Protein-containing Complex Binding Sphingolipid Binding
	Biological Process	Protein Ubiquitination Modification-dependent Protein Catabolic Process	Regulation Of Immunoglobulin Production Positive Regulation Of T Cell Cytokine Production Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Signal Transduction Involved In Regulation Of Gene Expression Protein Catabolic Process Positive Regulation Of Interleukin-2 Production Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Cellular Protein-containing Complex Assembly Response To Endoplasmic Reticulum Stress Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Protein-containing Complex Assembly Positive Regulation Of JUN Kinase Activity Positive Regulation Of JNK Cascade MRNA Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Protein-containing Complex Assembly Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Protein K63-linked Ubiquitination Cellular Response To Nitric Oxide Programmed Necrotic Cell Death Interleukin-17-mediated Signaling Pathway Negative Regulation Of Neuron Death Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of I-kappaB Phosphorylation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Activation of NF-kappaB in B cells ISG15 antiviral mechanism Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants ER-Phagosome pathway Downregulation of ERBB4 signaling Spry regulation of FGF signaling Downregulation of ERBB2:ERBB3 signaling Budding and maturation of HIV virion NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment DDX58/IFIH1-mediated induction of interferon-alpha/beta APC/C:Cdc20 mediated degradation of Cyclin B Autodegradation of Cdh1 by Cdh1:APC/C SCF-beta-TrCP mediated degradation of Emi1 APC/C:Cdc20 mediated degradation of Securin APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Cdc20:Phospho-APC/C mediated degradation of Cyclin A Membrane binding and targetting of GAG proteins Assembly Of The HIV Virion APC-Cdc20 mediated degradation of Nek2A Vpu mediated degradation of CD4 Vif-mediated degradation of APOBEC3G EGFR downregulation SCF(Skp2)-mediated degradation of p27/p21 Degradation of beta-catenin by the destruction complex TCF dependent signaling in response to WNT Downstream TCR signaling NRIF signals cell death from the nucleus p75NTR recruits signalling complexes NF-kB is activated and signals survival Regulation of activated PAK-2p34 by proteasome mediated degradation NOTCH1 Intracellular Domain Regulates Transcription Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Downregulation of SMAD2/3:SMAD4 transcriptional activity Downregulation of SMAD2/3:SMAD4 transcriptional activity SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Separation of Sister Chromatids Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Regulation of PLK1 Activity at G2/M Transition Constitutive Signaling by NOTCH1 PEST Domain Mutants Stimuli-sensing channels Constitutive Signaling by NOTCH1 HD Domain Mutants FCERI mediated NF-kB activation Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants NOTCH2 Activation and Transmission of Signal to the Nucleus Regulation of innate immune responses to cytosolic DNA Glycogen synthesis Autodegradation of the E3 ubiquitin ligase COP1 Deactivation of the beta-catenin transactivating complex Myoclonic epilepsy of Lafora ABC-family proteins mediated transport Circadian Clock TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 AUF1 (hnRNP D0) binds and destabilizes mRNA Asymmetric localization of PCP proteins Degradation of AXIN Degradation of DVL Regulation of FZD by ubiquitination PINK1-PRKN Mediated Mitophagy N-glycan trimming in the ER and Calnexin/Calreticulin cycle Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Dectin-1 mediated noncanonical NF-kB signaling CLEC7A (Dectin-1) signaling Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'on' state Hedgehog 'on' state Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Negative regulation of FGFR3 signaling Negative regulation of FGFR4 signaling Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis Regulation of RAS by GAPs TNFR2 non-canonical NF-kB pathway Negative regulation of MAPK pathway Regulation of necroptotic cell death NIK-->noncanonical NF-kB signaling Defective CFTR causes cystic fibrosis MAP3K8 (TPL2)-dependent MAPK1/3 activation HDR through Homologous Recombination (HRR) MAPK6/MAPK4 signaling UCH proteinases UCH proteinases Josephin domain DUBs Ub-specific processing proteases Ovarian tumor domain proteases Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Processing of DNA double-strand break ends DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation Regulation of TP53 Degradation Regulation of TP53 Activity through Methylation Negative regulation of MET activity CDT1 association with the CDC6:ORC:origin complex Orc1 removal from chromatin CDK-mediated phosphorylation and removal of Cdc6 Cyclin D associated events in G1 G2/M Checkpoints Stabilization of p53 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Ubiquitin-dependent degradation of Cyclin D PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 The role of GTSE1 in G2/M progression after G2 checkpoint FBXL7 down-regulates AURKA during mitotic entry and in early mitosis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Downregulation of ERBB2 signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes Synthesis of active ubiquitin: roles of E1 and E2 enzymes E3 ubiquitin ligases ubiquitinate target proteins InlB-mediated entry of Listeria monocytogenes into host cell InlB-mediated entry of Listeria monocytogenes into host cell InlA-mediated entry of Listeria monocytogenes into host cells ROS sensing by NFE2L2 RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity Regulation of RUNX3 expression and activity Regulation of PTEN localization Regulation of PTEN stability and activity Neddylation ER Quality Control Compartment (ERQC) Regulation of expression of SLITs and ROBOs Regulation of expression of SLITs and ROBOs NOTCH3 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus TICAM1-dependent activation of IRF3/IRF7 TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling Peroxisomal protein import Peroxisomal protein import Regulation of signaling by CBL Endosomal Sorting Complex Required For Transport (ESCRT) Iron uptake and transport Negative regulators of DDX58/IFIH1 signaling Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Negative regulation of NOTCH4 signaling Chaperone Mediated Autophagy Late endosomal microautophagy Prevention of phagosomal-lysosomal fusion Modulation by Mtb of host immune system Alpha-protein kinase 1 signaling pathway Aggrephagy Aggrephagy RAS processing Pexophagy Maturation of protein E Maturation of protein E Inactivation of CSF3 (G-CSF) signaling Negative regulation of FLT3 FLT3 signaling by CBL mutants Regulation of BACH1 activity TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Amyloid fiber formation Antigen processing: Ubiquitination & Proteasome degradation	Caspase activation via Death Receptors in the presence of ligand Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway TNFR2 non-canonical NF-kB pathway Regulation of necroptotic cell death TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway Ub-specific processing proteases Dimerization of procaspase-8 TNF signaling TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation Defective RIPK1-mediated regulated necrosis
Drugs		N-Formylmethionine
Diseases
GWAS		HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 29403010 33339817) Total cholesterol levels ( 29403010)	Platelet distribution width ( 32888494)
Interacting Genes		642 interacting genes: ABCB7 ABL1 ABRAXAS1 ABRAXAS2 ACTA1 ACTC1 ACTL8 ADH7 ADRM1 AGO2 AGRN AGTPBP1 ALG1 AMFR AMPH ANAPC1 ANAPC11 ANAPC2 ANAPC7 ANGPTL3 ANKIB1 ANKRD13A ANKRD13B ANKRD13D ANKRD30A ANKS1A ANKS1B ANP32E ANTXR1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 AREL1 ARIH1 ARIH2 ARMC1 ARRB2 ASB11 ASB2 ASCC2 ASCC3 ASXL1 ASXL2 ATP5PD ATXN3 ATXN3L ATXN7L3 B3GALT1 BABAM1 BABAM2 BAP1 BARD1 BARX1 BCAS2 BCR BECN1 BFAR BIN1 BIRC2 BIRC3 BRAP BRCA1 BRCC3 BRF1 BSG BTD BTRC C8orf34 CAPN15 CASP8 CAVIN1 CAVIN3 CBL CBLB CBLC CBR1 CBR3 CCDC50 CCDC92 CD2 CD2AP CDC20 CDC42 CDC45 CDH2 CDH22 CDIP1 CDK17 CDY1B CENPE CEP164 CEP192 CEP55 CEP83 CFAP36 CHD3 CHGA CHP1 CHUK CLN8 CLU COL1A1 COPB1 CPT1A CRACD CTBP2 CTRC CUEDC1 CUEDC2 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYLD DAXX DAZAP2 DCUN1D1 DDI1 DDI2 DDX19B DDX58 DECR2 DENR DESI1 DHX15 DLGAP4 DMBX1 DNAH7 DNAJB2 DNASE2B DOCK6 DPH1 DPY30 ECE2 EFS EIF3A EIF3H ELL ELOVL5 EP300 EPN1 EPN2 EPN3 EPS15 EPS15L1 ERCC6 ERGIC2 ERVK13-1 EXOSC8 FAAP20 FAF1 FAM168A FAN1 FAT1 FBH1 FBXL15 FBXO44 FCHO2 FETUB FGA FIS1 FLOT1 FLOT2 FSHR GARNL3 GBF1 GFPT2 GFUS GGA1 GGA3 GLG1 GRB2 GTF2H1 GTF2I GTF2IRD1 H2AC18 H2AC20 H2BC21 HACD1 HACD2 HAVCR1 HDAC5 HDAC6 HECW1 HERC1 HERC2 HERC3 HERC4 HGS HLTF HMGB1 HMGN2 HNRNPM HPDL HRNR HSD17B11 HSPA8 HSPG2 HUWE1 HYDIN HYDIN2 IDE IGF1R IKBKB IKBKG ILF3 ING1 INPPL1 IRS1 ISX ITCH ITGAV ITSN2 JOSD1 JOSD2 JUN KCTD7 KDM3B KEAP1 KEL KHDRBS1 KIAA0586 KLHL11 KLHL13 KLHL7 LACTB LAMA1 LAMA5 LAMB1 LAMC1 LAPTM5 LARP1B LIMA1 LINC02593 LNPK LTF LTN1 MACF1 MAD1L1 MALT1 MAP2K4 MAP3K7 MAP4 MAPRE2 MARCHF6 MARCHF7 MBOAT7 MDM2 MDM4 MDN1 MED15 MINDY1 MINDY2 MINDY3 MINDY4 MORC3 MRPL37 MTERF4 MTURN MUC16 MUC5B MUL1 MVP MYCBP MYL1 MYL3 MYO6 NAA10 NAT10 NBPF1 NBPF10 NBPF11 NBPF12 NBPF14 NBPF8 NBPF9 NBR1 NCK2 NCKAP5L NCOA6 NDC1 NDUFB9 NDUFS8 NEDD4 NEDD4L NEK8 NEURL3 NFIA NFX1 NPLOC4 NPM1 NPTN NSFL1C NSMCE1 NT5C1B NXPH4 OGT OPA3 OPRM1 OR7G3 OSBPL8 OTOG OTUB1 OTUB2 OTUD1 OTUD3 OTUD4 OTUD5 OTUD6A OTUD6B OTUD7A OTUD7B P4HTM PABPC4 PARP10 PCBP2 PCMTD1 PDCD6IP PDE12 PDS5A PEDS1 PELI1 PHF20L1 PHPT1 PIK3C2B PLAA PLEC PLEKHB2 PLSCR4 PMS2 POLH POLI POLR2C POP5 PPA1 PPARG PPARGC1A PPL PPM1D PRAME PRDX4 PRKCI PRKN PRPF8 PRR23B PSMA6 PSMD10 PSMD13 PSMD4 PSMD6 PSMD7 PSMD8 PTH1R PTOV1 PTPN2 PTPN23 PUS7L R3HDM4 RABEP1 RABEP2 RABGEF1 RAC1 RAD18 RAD23A RAD23B RAG1 RASAL2 RB1CC1 RBCK1 RC3H2 RCHY1 RECQL REV1 RFC1 RGPD3 RGS2 RIOK3 RLIM RNF11 RNF111 RNF114 RNF115 RNF123 RNF125 RNF126 RNF130 RNF144A RNF144B RNF145 RNF151 RNF165 RNF168 RNF169 RNF181 RNF182 RNF2 RNF216 RNF31 RNF38 RNF4 RNF5 RNF8 RPL12 RPL7L1 RPN1 RPS3 RTL8B RTL8C RTTN RYBP SBF2 SCD SDC4 SDCBP SDF2 SDK1 SEMA3F SEPTIN1 SEPTIN7P2 SFPQ SGK1 SGPP1 SH3KBP1 SHARPIN SLC27A2 SLC38A5 SLC5A6 SLIT2 SLX4 SMAD1 SMURF1 SMURF2 SMYD4 SNCA SNRNP25 SNRPA SNTB2 SNTG1 SOCS5 SPAG1 SPECC1L SPRTN SRPRB STAM STAM2 STAMBP STAMBPL1 STUB1 STX3 SUN5 SYNE2 TAB1 TAB2 TAC3 TAPBP TAX1BP1 TBC1D15 TBC1D5 TBXAS1 TCAF1 TCEAL1 TCHH TCOF1 TCP10L3 TDRD3 THG1L TIAM1 TMEM120A TMEM132A TMEM160 TMEM201 TMEM223 TNFAIP3 TNFAIP6 TNIP1 TNIP2 TNIP3 TNRC6A TNRC6C TOLLIP TOM1 TOM1L1 TOM1L2 TOPORS TOR1AIP2 TRAF2 TRAF3IP2 TRAF5 TRAF6 TRAFD1 TRAM1 TRIM17 TRIM21 TRIM23 TRIM25 TRIM32 TRIM36 TRIM39 TRIM5 TRIP12 TRIP4 TSG101 TTC28 TTC36 TTF2 TUBA3C TUBA3D TUBGCP2 UBA1 UBA2 UBA6 UBAC1 UBAC2 UBAP1 UBASH3A UBASH3B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2G2 UBE2J1 UBE2J2 UBE2N UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2S UBE2V1 UBE2V2 UBE3A UBFD1 UBL7 UBQLN1 UBQLN2 UBQLN4 UBR4 UBR5 UBXN1 UBXN6 UBXN7 UCHL1 UCHL3 UCHL5 UEVLD UFD1 UIMC1 ULK1 UNC79 UNC93B3 USP1 USP10 USP11 USP12 USP13 USP14 USP16 USP17L2 USP19 USP2 USP21 USP22 USP24 USP25 USP27X USP28 USP3 USP30 USP31 USP32 USP33 USP34 USP35 USP36 USP37 USP38 USP4 USP40 USP42 USP45 USP46 USP47 USP48 USP5 USP53 USP54 USP6 USP7 USP8 USP9X USP9Y VCP VCPIP1 VPS28 VPS36 VPS37A VPS37C VPS50 WARS1 WBP2 WDR33 WDR48 WFDC8 WRNIP1 WWP1 WWP2 XIAP XPNPEP1 XRCC5 XRCC6 YAF2 YARS2 YIPF5 YOD1 YWHAB YWHAG YWHAZ ZBTB1 ZC3H12A ZCWPW2 ZFAND2B ZFAND3 ZFAND5 ZFAND6 ZFYVE9 ZHX1 ZNF148 ZNF213 ZNF451 ZNF705G ZNF716 ZNF792 ZNRF1 ZNRF2 ZRANB1 ZUP1	380 interacting genes: AASDHPPT ABLIM1 ACTN3 AFF4 AGR2 AIMP2 AKR1B15 ALPL AMOTL2 ANKRD11 ANKRD36BP1 APEX2 APPL1 AQP1 ARHGEF6 ARNT2 ARSJ ASCC1 ATXN1 ATXN7 AXIN1 BAHD1 BANP BAZ2B BCL10 BCL6 BEX2 BEX3 BIRC2 BIRC3 BOD1L2 BYSL C22orf15 C2CD6 CALCOCO2 CAPN15 CASP8 CASP8AP2 CATSPER1 CAV1 CBX8 CCDC187 CCDC198 CCDC33 CCHCR1 CCNJL CD27 CD40 CDC20B CDC37 CDC42 CDCA3 CDK18 CDK9 CDKN1B CEP57L1 CFAP57 CFLAR CHCHD2 CHMP2B CHUK CREB5 CRY1 CRY2 CRYBA2 CTCF CWF19L2 CYB5R2 CYLD DDI1 DDX6 DGCR6 DLGAP5 DMTN DTNB DVL2 DVL3 EAF1 EBF2 EDAR EDARADD EFEMP1 EFHC1 EGFR EIF4G1 ELOA2 ENKD1 EP300 EP400 ERN1 ETV6 EWSR1 EXOC3-AS1 FADD FAM107A FAM120B FAM124B FAM161A FAM161B FAM214B FAM50B FAM90A1 FAM9A FARS2 FATE1 FBF1 FBXO28 FDXACB1 FLNA FLYWCH1 FNDC11 FNDC3B FOXN1 FXR1 FXR2 GABPB1 GAS8 GCA GCKR GEM GORASP2 GPANK1 GPKOW GRIPAP1 GSE1 GSG1 GSTP1 GSTZ1 HENMT1 HINFP HIVEP3 HOXA1 HOXB5 HSPA12B IKBKB IL15RA IMPDH2 INO80B IP6K3 IPO11 IQUB IRF4 ITPK1 ITPRIPL1 JUN KANK2 KANSL1 KIAA0408 KIAA1217 KIF26B KIFC3 KLF3 LENG1 LINC02875 LNX1 LNX2 LONRF1 LRRK2 LTBR LYSMD1 LZTS2 MACROH2A1 MALT1 MAP3K1 MAP3K14 MAP3K5 MAP3K8 MAP4K2 MAP4K5 MAPK9 MAPRE1 MAST2 MBLAC1 METTL13 MFAP1 MISP MKRN3 MORN3 MOS MPP3 MSRB2 MVP MYO15B NAB2 NATD1 NCAPH2 NEBL NECAP2 NEDD9 NEK6 NFIL3 NFKBID NGFR NHSL2 NIF3L1 NMUR2 NOXA1 NR2C2 NR4A1 NRF1 NRIP1 NUDT16L1 NUDT18 PACS2 PALS1 PCGF2 PCGF5 PDLIM7 PDZD4 PEG3 PGBD1 PIAS2 PIBF1 PIN1 PKN1 POLR3C POM121 PPL PPP1R18 PPP1R32 PRKAB2 PRKRIP1 PRPF18 PSMB1 PSMD9 PSME3IP1 PSMF1 QARS1 QRICH1 RAD23A RAD54L2 RALBP1 RANBP3 RAPGEF4 RASSF5 RBM41 RCOR3 RFX3 RGS14 RIBC2 RIN1 RIPK1 RIPK2 RIPK3 RIPPLY1 RIPPLY3 RNF146 RNF4 RRAS2 RSPH14 SAMD11 SCNM1 SETD5 SH2D4A SHC3 SIAH2 SMG9 SMURF2 SNAI1 SNRNP25 SOX13 SOX30 SOX5 SOX9 SPATA2 SPG21 SPHK1 SPRY2 SUMO1 SUMO1P1 SYT17 TAB1 TAB2 TAB3 TANK TAOK3 TBK1 TCAF1 TCEA2 TCEANC TCL1A TDP2 TEKT3 THAP7 THOP1 TICAM1 TIFA TIGD4 TLE5 TNF TNFAIP3 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF19 TNFRSF1A TNFRSF1B TNFRSF25 TNFRSF4 TNFRSF8 TNFRSF9 TNFSF4 TNFSF9 TNIK TRADD TRAF1 TRAF3 TRAF3IP2 TRAF5 TRAF6 TRAIP TRIM14 TRIM31 TRIM37 TRIM42 TRIM50 TROAP TRPC4AP TRPT1 TSC1 TSGA10IP TSHZ2 TSHZ3 TSSC4 TTC23 TXN UBC UBE2D1 UBE2D2 UBE2I UBE2N UBE2V1 UBE2V2 UBQLN4 UBXN11 USF1 USP2 USP4 USP53 USP7 UTP14C UTP23 VEZF1 VWA2 WASF1 YES1 YJU2B ZBTB16 ZBTB24 ZBTB25 ZBTB43 ZBTB49 ZC2HC1C ZFAND6 ZKSCAN3 ZMAT2 ZMYM5 ZNF205 ZNF250 ZNF35 ZNF410 ZNF417 ZNF438 ZNF488 ZNF544 ZNF572 ZNF574 ZNF646 ZNF648 ZNF655 ZNF662 ZNF688 ZNF774 ZSCAN23 ZSCAN32 ZSWIM3 ZZZ3
Entrez ID		7316	7186
HPRD ID		07038	03538
Ensembl ID		ENSG00000150991	ENSG00000127191
Uniprot IDs		P0CG48	A0A024R8H5 Q12933
PDB IDs		1C3T 1CMX 1D3Z 1F9J 1FXT 1G6J 1GJZ 1NBF 1OGW 1Q5W 1S1Q 1SIF 1TBE 1UBI 1UBQ 1UD7 1XD3 1XQQ 1YX5 1YX6 1ZGU 1ZO6 2AYO 2BGF 2DEN 2FUH 2G45 2GBJ 2GBK 2GBM 2GBN 2GBR 2GMI 2HTH 2IBI 2J7Q 2JF5 2JRI 2JY6 2JZZ 2K25 2K6D 2K8B 2K8C 2KDF 2KHW 2KJH 2KLG 2KN5 2KX0 2L3Z 2LD9 2LVO 2LVP 2LVQ 2LZ6 2MBO 2MBQ 2MCN 2MI8 2MJ5 2MOR 2MRE 2MWS 2N2K 2NR2 2O6V 2OJR 2PE9 2PEA 2RR9 2RU6 2W9N 2WDT 2XEW 2Y5B 2Z59 2ZCB 2ZVN 2ZVO 3A33 3ALB 3AUL 3B08 3B0A 3BY4 3C0R 3DVG 3DVN 3EEC 3EFU 3EHV 3H7P 3H7S 3HM3 3I3T 3IFW 3IHP 3JSV 3JVZ 3JW0 3K9O 3K9P 3KVF 3KW5 3LDZ 3MHS 3MTN 3N30 3N32 3N3K 3NS8 3O65 3OFI 3OJ3 3OJ4 3ONS 3PRM 3PT2 3PTF 3Q3F 3RUL 3TMP 3U30 3UGB 3V6C 3V6E 3VFK 3VUW 3VUX 3VUY 3WXE 3WXF 3ZLZ 3ZNH 3ZNI 3ZNZ 4AP4 4AUQ 4BOS 4BOZ 4BVU 4DDG 4DDI 4DHJ 4DHZ 4FJV 4HK2 4HXD 4I6L 4I6N 4IG7 4IUM 4JQW 4K1R 4K7S 4K7U 4K7W 4KSK 4KSL 4LCD 4LDT 4MDK 4MM3 4MSM 4MSQ 4NQK 4UN2 4V3K 4V3L 4WZP 4XOK 4XOL 4ZQS 5A5B 5AF4 5AF5 5AF6 5AIT 5AIU 5B83 5C7J 5C7M 5E6J 5H07 5NL4 5NLF 5NLI 5NMC 5OE7 5OHV 5OXH 5OXI 5UDH 5WQ4 5ZQ3 5ZQ4 5ZQ5 5ZQ6 5ZQ7 6A43 6A44 6AQR 6B7M 6B7O 6EQI 6K2U 6KBE 6N13 6N6R 6NQA 6NXK 6OI4 6P5B 6Q00 6QML 6RYA 6S53 6SQR 6T7F 6T9L 6TNF 6TTU 6TUV 6TXB 6ULH 6UMP 6UMS 6UPU 6V5D 6VAE 6VAF 6VEN 6W9D 6W9R 6W9S 6WJD 6WKR 6WTG 7B5L 7B5M 7B5N 7BBD 7BBF 7BXG 7K6P 7K6Q	1CA4 1CA9 1CZY 1CZZ 1D00 1D01 1D0A 1D0J 1F3V 1QSC 3KNV 3M06 3M0A 3M0D
Enriched GO Terms of Interacting Partners?
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