PPID and S100A6

Number of citations of the paper that reports this interaction (PubMedID 20188096)
12

Data Source:
BioGRID (pull down, affinity chromatography technology)

		PPID	S100A6
Description		peptidylprolyl isomerase D	S100 calcium binding protein A6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Ruffle Extracellular Region Nucleus Nuclear Envelope Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Cyclosporin A Binding Estrogen Receptor Binding Hsp70 Protein Binding Heat Shock Protein Binding Hsp90 Protein Binding	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Peptidyl-prolyl Isomerization Protein Folding Apoptotic Process Protein Transport Viral Release From Host Cell Lipid Droplet Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Chaperone-mediated Protein Folding Protein-containing Complex Assembly Cellular Response To UV-A	Signal Transduction Axonogenesis Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation
Pathways		ESR-mediated signaling
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Blood protein levels ( 30072576 28240269) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Serum metabolite levels ( 23093944)	HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		21 interacting genes: APP BCL2 CSNK2B ESR1 FBXO25 FES HAP1 HSF1 HSP90AA1 HSP90AB1 HSPA8 KAT7 LARP1 LNX1 PLK1 S100A1 S100A2 S100A6 SLC25A4 SMURF2 TRIM27	17 interacting genes: ANXA11 ANXA2 CACYBP CEP20 CEP43 FAM25A FAM25C FAM25G FKBP4 GAPDH MDM2 OFD1 PEX5 PPID S100B SUGT1 TP53
Entrez ID		5481	6277
HPRD ID		11875	00237
Ensembl ID		ENSG00000171497	ENSG00000197956
Uniprot IDs		E5KN55 Q08752	P06703
PDB IDs			1K8U 1K96 1K9K 1K9P 2M1K 4YBH
Enriched GO Terms of Interacting Partners?
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