PPID and SLC25A4

Number of citations of the paper that reports this interaction (PubMedID 12149099)
86

Data Source:
HPRD (in vitro)

		PPID	SLC25A4
Description		peptidylprolyl isomerase D	solute carrier family 25 member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Integral Component Of Plasma Membrane Membrane Integral Component Of Mitochondrial Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Cyclosporin A Binding Estrogen Receptor Binding Hsp70 Protein Binding Heat Shock Protein Binding Hsp90 Protein Binding	ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Oxidative Phosphorylation Uncoupler Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Peptidyl-prolyl Isomerization Protein Folding Apoptotic Process Protein Transport Viral Release From Host Cell Lipid Droplet Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Chaperone-mediated Protein Folding Protein-containing Complex Assembly Cellular Response To UV-A	Mitochondrial Genome Maintenance Generation Of Precursor Metabolites And Energy Apoptotic Mitochondrial Changes Adenine Transport ADP Transport Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Necroptotic Process Mitochondrial ADP Transmembrane Transport Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Adaptive Thermogenesis
Pathways		ESR-mediated signaling	Mitochondrial protein import Mitochondrial protein import Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs			ATP Clodronic acid Etidronic acid [3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium Carboxyatractyloside Tetrastearoyl cardiolipin Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS		Blood protein levels ( 30072576 28240269) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Serum metabolite levels ( 23093944)
Interacting Genes		21 interacting genes: APP BCL2 CSNK2B ESR1 FBXO25 FES HAP1 HSF1 HSP90AA1 HSP90AB1 HSPA8 KAT7 LARP1 LNX1 PLK1 S100A1 S100A2 S100A6 SLC25A4 SMURF2 TRIM27	7 interacting genes: AR BAX NFKBIA NR3C1 PPID PPIF PRKCE
Entrez ID		5481	291
HPRD ID		11875	00058
Ensembl ID		ENSG00000171497	ENSG00000151729
Uniprot IDs		E5KN55 Q08752	A0A0S2Z3H3 P12235
PDB IDs
Enriched GO Terms of Interacting Partners?
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