PPP1R12C and THOC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PPP1R12C	THOC1
Description		protein phosphatase 1 regulatory subunit 12C	THO complex 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Phosphatase Regulator Activity Protein Kinase Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Signal Transduction Negative Regulation Of Catalytic Activity	Regulation Of DNA Recombination RNA Processing MRNA Processing MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)
Interacting Genes		27 interacting genes: ATP6V1H ATXN7 BHLHA9 C1orf109 CACNA1A CCDC185 CDC42BPA EHHADH EXOC3 FMR1 FXR1 FXR2 IL16 IMP3 MPRIP MYL2 NOD2 NXF1 PAFAH1B2 PPP1CB RBM17 SMAD3 SMARCA2 SPECC1L THOC1 TSFM USHBP1	28 interacting genes: AGR2 AKAP9 ATP1B1 BHLHB9 CTAG1A CTAG1B DHX8 EXOC5 FRA10AC1 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C RABGEF1 RB1 REL SAP30BP SF3B2 TADA2A TRIM27 TRIM54 TYMS USHBP1 WDR77 ZMYND12
Entrez ID		54776	9984
HPRD ID		11452	09498
Ensembl ID		ENSG00000125503	ENSG00000079134
Uniprot IDs		Q9BZL4	Q96FV9
PDB IDs			1WXP 7APK
Enriched GO Terms of Interacting Partners?
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