NUP54 and NUTF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, pull down)
HPRD (in vivo)

		NUP54	NUTF2
Description		nucleoporin 54	nuclear transport factor 2
Image
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Membrane Nuclear Pore Central Transport Channel	Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytosol Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Targeting NLS-bearing Protein Import Into Nucleus Nuclear Pore Organization Protein Localization To Nuclear Inner Membrane Regulation Of Protein Import Into Nucleus MRNA Transport	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus MRNA Transport Protein Localization To Nuclear Pore Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Hippocampal volume ( 29274321)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		50 interacting genes: AGR2 AP1B1 AP2B1 APC BPIFA1 C14orf119 C1orf109 C21orf91 CCDC85B CCHCR1 CDC23 CENPH DCTN3 DGCR6 EFHC1 EIF3F EXOC1 EXOC8 GOLIM4 HAUS1 HAUS8 HGS HOMER1 IFT20 KPNA1 KPNB1 KRT15 KRT27 KRT33B NFKBID NR3C1 NUP62 NUTF2 OGT OIP5 PKNOX2 SEPTIN11 SMYD3 SOHLH1 SPG21 SSR1 TACC3 TCHP TEKT1 TEX12 THAP6 TPM3 TRIM54 VPS37C ZWINT	55 interacting genes: BEND7 BRWD1 CAMK2G CANX CCDC106 CCDC150 CCDC158 CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B GLRX2 HMG20A HMG20B KHDC4 KPNB1 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NFAT5 NME1 NME4 NRIP3 NUP153 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SF3B3 SPATC1L SPRY4 TERF2 TEX35 THAP11 THAP3 TLE5 UBAP2 WWP2 YAF2 ZMAT2
Entrez ID		53371	10204
HPRD ID		06352	12050
Ensembl ID		ENSG00000138750	ENSG00000102898
Uniprot IDs		Q7Z3B4	A0A024R6Y2 P61970
PDB IDs		4JNU 4JNV 4JO7 4JO9 5IJN 5IJO	1GY5
Enriched GO Terms of Interacting Partners?
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