BTBD1 and TOP1

  • Number of citations of the paper that reports this interaction (PubMedID 11818025)
  • 10
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

BTBD1

TOP1

Description BTB domain containing 1 DNA topoisomerase I
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic obstructive pulmonary disease ( 30804561)
  • Estimated glomerular filtration rate ( 31152163)
  • Kawasaki disease ( 21326860)
  • Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
  • Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
  • Brain morphology (MOSTest) ( 32665545)
  • Cholesterol, total ( 24097068 20686565)
  • Fasting glucose ( 33402679)
  • Hemoglobin ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • LDL cholesterol ( 24097068 20686565)
  • LDL cholesterol levels ( 28334899)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Male-pattern baldness ( 28196072)
  • Metabolite levels ( 23823483)
  • PR interval ( 32439900)
  • Red blood cell count ( 32888494)
  • Refractive error ( 32231278)
  • Total cholesterol levels ( 28334899)
  • Urate levels ( 31578528)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 11 interacting genes: CUL3 LNX1 MPP3 MTNR1B NTAQ1 PSMD5 RNF4 TOP1 TRAF7 TRIM5 TULP3 61 interacting genes: APAF1 APP ATM BARD1 BRCA1 BRD2 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PIAS4 PPP2R2B PRB1 PRKDC PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRPK2 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I XRCC5 XRCC6
Entrez ID 53339 7150
HPRD ID 12251 00535
Ensembl ID ENSG00000064726 ENSG00000198900
Uniprot IDs A0A024R224 Q9H0C5 P11387 Q9BVT2
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?