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PKP2 and MTUS2
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
484
Data Source:
BioGRID
(two hybrid, two hybrid, two hybrid)
PKP2
MTUS2
Description
plakophilin 2
microtubule associated scaffold protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Cornified Envelope
Nucleus
Nucleoplasm
Cytoplasm
Intermediate Filament
Plasma Membrane
Cell-cell Junction
Adherens Junction
Intercalated Disc
Integral Component Of Membrane
Cell Junction
Desmosome
Messenger Ribonucleoprotein Complex
Nucleus
Cytoplasm
Centrosome
Cytoplasmic Microtubule
Molecular Function
Protein Kinase C Binding
Protein Binding
Sodium Channel Regulator Activity
Intermediate Filament Binding
Transmembrane Transporter Binding
Alpha-catenin Binding
Cadherin Binding
Molecular Adaptor Activity
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Protein Binding
Microtubule Binding
Protein Homodimerization Activity
Biological Process
Desmosome Assembly
Desmosome Organization
Cell-cell Junction Assembly
Heart Development
Positive Regulation Of Sodium Ion Transport
Intermediate Filament Bundle Assembly
Maintenance Of Animal Organ Identity
Ventricular Cardiac Muscle Tissue Morphogenesis
Protein Localization To Plasma Membrane
Cardiac Muscle Cell Action Potential Involved In Contraction
Ventricular Cardiac Muscle Cell Action Potential
Cell-cell Signaling Involved In Cardiac Conduction
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Regulation Of Heart Rate By Cardiac Conduction
Cell-cell Adhesion
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
Keratinization
Formation of the cornified envelope
Drugs
Diseases
GWAS
Atrial fibrillation (
30061737
29892015
)
Blood protein levels (
30072576
)
Body mass index (change over time) in lung cancer (
28044437
)
Methadone dose in opioid dependence (
28115739
)
Obesity-related traits (
23251661
)
Parkinson's disease (
32201043
27182965
)
Periodontal disease related phenotype (PCT5) (
26962152
)
Prevalent atrial fibrillation (
28416818
)
HDL cholesterol levels in HIV infection (
33109212
)
Hypertrophic cardiomyopathy (sarcomere positive) (
33495597
)
Insomnia (caffeine-induced) (
22754043
)
Obesity-related traits (
23251661
)
Triptolide cytotoxicity (
26121980
)
Interacting Genes
45 interacting genes:
ACTN3
AKAP9
ARMC8
CARD9
CASK
CCDC120
CCDC125
CCHCR1
CTNNB1
DDX11
DMRTB1
DSC1
DSC2
DSG1
DSG2
DSP
FHL3
GOLGA2
GRIPAP1
GTF2IRD1
HOOK2
HSPB2
ITPR2
JUP
KDM5A
KLC4
KRT18
KRT31
KRT5
MAGOHB
MARK3
MTUS2
NCKIPSD
NDEL1
PIBF1
PLEKHG4
POLR3A
RABEP1
RBM5
ROPN1
SINHCAF
SMAD9
SPTA1
TEKT4
YWHAG
327 interacting genes:
-
ABHD15
ACSM1
AEN
AFF4
AKT1
ANKRD11
ANKS1A
AQP1
ARL4A
ARNT2
AXIN1
BANF2
BARD1
BCL6
BEX2
BMP7
BYSL
C19orf44
C1orf109
C1orf216
C1orf35
C21orf58
C2CD6
C8orf34
CACNB3
CATIP
CATSPER1
CBX8
CCAR1
CCDC116
CCDC120
CCDC146
CCDC17
CCDC185
CCDC187
CCDC198
CCDC6
CCDC60
CCHCR1
CDC20B
CDC5L
CDC7
CDC73
CDK18
CDK5R1
CDKL3
CDKN1A
CDKN1B
CEP57L1
CEP95
CERK
CHIC2
CNNM3
COG2
CREB5
CRY2
CSF1
CTSZ
CWF19L2
CXCL11
CXCL16
CYSLTR2
DCDC2B
DCTN4
DCX
DDX6
DHRS1
DLGAP4
DLGAP5
DMRT3
DOCK2
DTNB
EHHADH
EIF3D
ENKD1
ENPP7
EXOC8
FAM107A
FAM110A
FAM124B
FAM13C
FAM161A
FAM161B
FAM71E2
FAM74A4
FAM90A1
FASTKD5
FBXL18
FBXO34
FBXW5
FCHSD2
FHL3
FLYWCH1
FNDC11
FXR1
GADD45GIP1
GAL3ST2
GAS2L2
GEM
GGN
GNL3L
GOLGA2P11
GPKOW
GRAP2
GSTP1
GTF2I
GTPBP10
HAPLN2
HAUS1
HBZ
HCK
HDAC4
HOXB5
HOXB9
HSF2
ICAM4
IL16
INO80B
IQCE
ITGB4
ITGB5
ITSN1
JMY
JOSD1
JRK
KANK2
KAT5
KIF1A
KIFC3
KRT6A
KRT75
KRT76
LENG1
LIMS2
LINC00636
LMO2
LMO3
LMO4
LNX1
LRR1
LYSMD1
MAGEA8
MARK4
MBD3
METTL17
MFAP1
MOS
MRPL11
MTMR6
MYO15B
MYOM1
MYPOP
NDEL1
NDOR1
NEFL
NELFE
NHSL2
NTAQ1
NUBPL
NUDT10
NXF1
ODAD3
ODF1
PCDHB14
PDE4DIP
PDZD4
PIBF1
PIN1
PKN1
PKN3
PKP2
PLEKHN1
PLK4
PLSCR4
POLDIP2
POLDIP3
PPHLN1
PPP1R18
PRKAA1
PRKAA2
PRPF18
PRPF31
PRR35
PSMA1
PSMB1
PTCD1
PTK7
PTPMT1
RAB3IL1
RALY
RANBP3L
RAP1B
RASAL3
RASD1
RBM41
RCOR3
RGS2
RHPN1
RIBC2
RNF6
ROBO3
RPA1
RPL9
RPS19BP1
RTP5
SAMD4A
SCEL
SCNM1
SDCBP
SELENOM
SETD5
SH2D4A
SH3RF2
SHFL
SLC22A5
SLC23A1
SLC25A42
SLC25A48
SLC25A6
SLIRP
SMARCD1
SMARCE1
SMG9
SNAI1
SNHG11
SNRPA
SNRPB2
SNW1
SPATA8
SPATC1L
SPG21
SPG7
STK16
SYT6
TACO1
TAF13
TBC1D22B
TCEA2
TCEANC
TCHP
TEAD4
TEPSIN
THAP7
TLE5
TNIP3
TNNI1
TP53RK
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC23
TTLL10
TULP2
TXN2
UBTFL1
USP2
USP22
UTP14C
VASN
WAC
ZBTB16
ZBTB38
ZBTB47
ZC2HC1C
ZFC3H1
ZFHX3
ZFP1
ZFP2
ZFP64
ZFYVE21
ZMAT2
ZMYND10
ZNF124
ZNF136
ZNF17
ZNF20
ZNF224
ZNF23
ZNF230
ZNF232
ZNF239
ZNF250
ZNF266
ZNF3
ZNF329
ZNF337
ZNF35
ZNF408
ZNF410
ZNF414
ZNF415
ZNF417
ZNF426
ZNF438
ZNF439
ZNF440
ZNF48
ZNF490
ZNF497
ZNF512B
ZNF557
ZNF564
ZNF572
ZNF580
ZNF581
ZNF587
ZNF599
ZNF607
ZNF613
ZNF624
ZNF648
ZNF655
ZNF669
ZNF670
ZNF696
ZNF76
ZNF764
ZNF774
ZNF775
ZNF785
ZNF792
ZNF837
ZNF844
ZSCAN12
ZSCAN26
Entrez ID
5318
23281
HPRD ID
04177
11108
Ensembl ID
ENSG00000057294
ENSG00000132938
Uniprot IDs
Q99959
Q5JR59
PDB IDs
3TT9
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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