RAB8B and RALA

Number of citations of the paper that reports this interaction (PubMedID 10889189)
14

Data Source:
HPRD (in vivo, in vitro)

		RAB8B	RALA
Description		RAB8B, member RAS oncogene family	RAS like proto-oncogene A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Nuclear Body Trans-Golgi Network Transport Vesicle Phagocytic Vesicle Membrane Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Recycling Endosome Membrane Extracellular Exosome	Mitochondrion Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding GDP Binding TPR Domain Binding	GTPase Activity G Protein Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Cellular Response To Insulin Stimulus Protein Import Into Peroxisome Membrane Golgi Vesicle Fusion To Target Membrane Positive Regulation Of Corticotropin Secretion Cilium Assembly Protein Localization To Plasma Membrane Cell-substrate Junction Organization	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Mitochondrial Fission
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Phosphoaminophosphonic acid guanylate ester Guanosine-5'-Diphosphate	Guanosine-5'-Diphosphate
Diseases
GWAS		Refractive error ( 32231278) Serum metabolite levels ( 23093944) Social communication problems ( 24564958)
Interacting Genes		8 interacting genes: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM VPS13C	36 interacting genes: ACTB AKAP10 ARF1 C1QC CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GCK GLS2 HOXA2 HSPB1 INHBA LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		51762	5898
HPRD ID		11476	01549
Ensembl ID		ENSG00000166128	ENSG00000006451
Uniprot IDs		Q92930	P11233
PDB IDs			1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O
Enriched GO Terms of Interacting Partners?
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