RAB8B and RAB3IP

Number of citations of the paper that reports this interaction (PubMedID 12221131)
84

Data Source:
HPRD (two hybrid)

		RAB8B	RAB3IP
Description		RAB8B, member RAS oncogene family	RAB3A interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Nuclear Body Trans-Golgi Network Transport Vesicle Phagocytic Vesicle Membrane Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Recycling Endosome Membrane Extracellular Exosome	Nucleus Microtubule Organizing Center Cytosol Lamellipodium Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding GDP Binding TPR Domain Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Cellular Response To Insulin Stimulus Protein Import Into Peroxisome Membrane Golgi Vesicle Fusion To Target Membrane Positive Regulation Of Corticotropin Secretion Cilium Assembly Protein Localization To Plasma Membrane Cell-substrate Junction Organization	Protein Targeting To Membrane Exocytosis Regulation Of Catalytic Activity Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs		Phosphoaminophosphonic acid guanylate ester Guanosine-5'-Diphosphate
Diseases
GWAS		Refractive error ( 32231278) Serum metabolite levels ( 23093944) Social communication problems ( 24564958)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		8 interacting genes: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM VPS13C	33 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A GPD2 KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76
Entrez ID		51762	117177
HPRD ID		11476	10565
Ensembl ID		ENSG00000166128	ENSG00000127328
Uniprot IDs		Q92930	Q96QF0
PDB IDs			4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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