ATP8A2 and UIMC1

Number of citations of the paper that reports this interaction (PubMedID 17621610)
79

Data Source:
BioGRID (enzymatic study)

		ATP8A2	UIMC1
Description		ATPase phospholipid transporting 8A2	ubiquitin interaction motif containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleoplasm Endosome Golgi Apparatus Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Nuclear Body BRCA1-A Complex
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding ATP Hydrolysis Activity Phosphatidylethanolamine Flippase Activity ATPase-coupled Intramembrane Lipid Transporter Activity Phosphatidylserine Flippase Activity	DNA Binding Protein Binding Histone Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Involuntary Skeletal Muscle Contraction Axonogenesis Aging Negative Regulation Of Cell Population Proliferation Retina Layer Formation Positive Regulation Of Neuron Projection Development Response To Auditory Stimulus Positive Regulation Of Multicellular Organism Growth Inner Ear Morphogenesis Eating Behavior Skin Development Phospholipid Translocation Neuron Development Neuromuscular Process Controlling Posture Detection Of Light Stimulus Involved In Visual Perception Neurofilament Cytoskeleton Organization Positive Regulation Of Phospholipid Translocation Aminophospholipid Translocation	Double-strand Break Repair Mitotic G2 DNA Damage Checkpoint Signaling Response To Ionizing Radiation Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination
Pathways		Ion transport by P-type ATPases	Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Breast milk fatty acid composition (infant genotype effect) ( 29514873) Breast milk fatty acid composition (maternal genotype effect) ( 29514873) Common carotid intima-media thickness ( 29206233) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Eating disorders ( 23568457) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft palate ( 31609978)	Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201 26414677 29773799) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: UIMC1	23 interacting genes: ABRAXAS1 ATP8A2 BRCC3 CEP57 CREBBP DVL2 DYNLT3 ECPAS ESR1 FANCG H2AC20 INO80B MDC1 NR6A1 RAD23A SKIL SUMO2 TP53 UBB UBC USP13 WBP2 ZMYM3
Entrez ID		51761	51720
HPRD ID		05795	11482
Ensembl ID		ENSG00000132932	ENSG00000087206
Uniprot IDs		B7Z880 Q6ZU25 Q9NTI2	A0A024R7R0 Q96RL1
PDB IDs			2MKF 2MKG 2N9E 2RR9
Enriched GO Terms of Interacting Partners?
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