SUFU and BTRC

  • Number of citations of the paper that reports this interaction (PubMedID 10564661)
  • 60
  • Data Source:
  • HPRD (in vivo, in vitro)

SUFU

BTRC

Description SUFU negative regulator of hedgehog signaling beta-transducin repeat containing E3 ubiquitin protein ligase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergy ( 27182965)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Body shape index ( 34021172)
  • Brain morphology (MOSTest) ( 32665545)
  • Creatinine levels ( 29403010)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Eosinophil counts ( 32888494)
  • Estimated glomerular filtration rate ( 30604766)
  • Glomerular filtration rate ( 29403010)
  • Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Nickel levels ( 26025379)
  • Optic disc size ( 31809533)
  • Platelet count ( 32888494)
  • Prostate cancer ( 23535732)
  • Refractive error ( 32231278)
  • Sum eosinophil basophil counts ( 27863252)
  • Systolic blood pressure ( 30578418)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • White blood cell count ( 29403010)
  • Diastolic blood pressure ( 30224653)
  • Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
  • Red blood cell count ( 29403010)
  • Red cell distribution width ( 32888494)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Walking pace ( 33128006)
Interacting Genes 51 interacting genes: ABI3 AKR1C1 BFSP2 BTRC CRTC2 CRX DISC1 EDA2R FBXL17 FXR1 GLI1 GLI2 GLI3 GLIS3 HDX HMGA1 HNRNPA1 ITCH KRT27 KRT75 L3MBTL3 LAMTOR3 LCA5 LGALS3 LZTS1 MAGEL2 MEOX2 MID1IP1 NCOA3 PEX26 PIAS1 QPRT RBPJ RCN3 RNF19A SAP18 SETDB1 SH3RF1 SLC41A3 STK36 STX19 TLE5 ZIC1 ZNF114 ZNF219 ZNF263 ZNF330 ZNF446 ZNF763 ZNF764 ZSCAN18 86 interacting genes: AGO2 AMER1 ATF4 AXIN1 AXIN2 BORA CCND1 CCNE1 CDC25A CDC34 CDK1 CENPW CHPF CHUK CP CTNNB1 CUL1 DBN1 DEPTOR DLGAP5 DPCD E2F1 FBXW11 FBXW2 FOXO3 FZR1 GHR GLI2 GLI3 GSK3B HIPK2 HNRNPC HNRNPK HNRNPU ICE1 IL10RA JUP KDR KMT5A LINC00511 LPCAT1 MCL1 MDM2 MYB MYC NFE2 NFE2L2 NFKB1 NFKB2 NFKBIA NFKBIB NHSL2 PAQR3 PCDH8 PDCD4 PER2 PLK4 PRDX1 PSMA3 PSMD4 RASSF5 RCAN1 RELA RNF7 SKP1 SLC7A11-AS1 SMAD3 SMAD4 SMURF1 SMURF2 SUFU TACC1 TAFAZZIN TIAM1 TP63 TRIB2 TRIM36 TRIM9 TSPAN15 UBC UBE2D2 UBE2R2 UBQLN2 WEE1 XRCC1 ZC3H12A
Entrez ID 51684 8945
HPRD ID 06124 04596
Ensembl ID ENSG00000107882 ENSG00000166167
Uniprot IDs A0A223LX15 Q9UMX1 A0A0S2Z4P6 B2R8L3 B7Z3H4 Q68DS0 Q9Y297
PDB IDs 1M1L 4BL8 4BL9 4BLA 4BLB 4BLD 4KM8 4KM9 4KMD 4KMH 1P22 2P64 6M90 6M91 6M92 6M93 6M94 6TTU
Enriched GO Terms of Interacting Partners?
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