BTRC and FBXW2

  • Number of citations of the paper that reports this interaction (PubMedID 28514442)
  • 406
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology)

BTRC

FBXW2

Description beta-transducin repeat containing E3 ubiquitin protein ligase F-box and WD repeat domain containing 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 30224653)
  • Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
  • Red blood cell count ( 29403010)
  • Red cell distribution width ( 32888494)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Walking pace ( 33128006)
  • Hip circumference adjusted for BMI ( 25673412)
Interacting Genes 86 interacting genes: AGO2 AMER1 ATF4 AXIN1 AXIN2 BORA CCND1 CCNE1 CDC25A CDC34 CDK1 CENPW CHPF CHUK CP CTNNB1 CUL1 DBN1 DEPTOR DLGAP5 DPCD E2F1 FBXW11 FBXW2 FOXO3 FZR1 GHR GLI2 GLI3 GSK3B HIPK2 HNRNPC HNRNPK HNRNPU ICE1 IL10RA JUP KDR KMT5A LINC00511 LPCAT1 MCL1 MDM2 MYB MYC NFE2 NFE2L2 NFKB1 NFKB2 NFKBIA NFKBIB NHSL2 PAQR3 PCDH8 PDCD4 PER2 PLK4 PRDX1 PSMA3 PSMD4 RASSF5 RCAN1 RELA RNF7 SKP1 SLC7A11-AS1 SMAD3 SMAD4 SMURF1 SMURF2 SUFU TACC1 TAFAZZIN TIAM1 TP63 TRIB2 TRIM36 TRIM9 TSPAN15 UBC UBE2D2 UBE2R2 UBQLN2 WEE1 XRCC1 ZC3H12A 11 interacting genes: BTRC CDC34 CLVS2 CTNNB1 CUL1 EXOSC2 MSX2 MYB SKP1 TRIM54 UBE2D2
Entrez ID 8945 26190
HPRD ID 04596 09950
Ensembl ID ENSG00000166167 ENSG00000119402
Uniprot IDs A0A0S2Z4P6 B2R8L3 B7Z3H4 Q68DS0 Q9Y297 B4DT60 Q9UKT8
PDB IDs 1P22 2P64 6M90 6M91 6M92 6M93 6M94 6TTU
Enriched GO Terms of Interacting Partners?
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