CHMP3 and CHMP2A

Number of citations of the paper that reports this interaction (PubMedID 16730941)
66

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		CHMP3	CHMP2A
Description		charged multivesicular body protein 3	charged multivesicular body protein 2A
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Early Endosome Late Endosome Multivesicular Body Cytosol Plasma Membrane Midbody Cytoplasmic Vesicle Late Endosome Membrane Extracellular Exosome	Chromatin ESCRT III Complex Nuclear Envelope Multivesicular Body Cytosol Membrane Membrane Coat Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylcholine Binding Ubiquitin-specific Protease Binding	Protein Binding Protein Domain Specific Binding Phosphatidylcholine Binding
	Biological Process	Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Macroautophagy Positive Regulation Of Cytokinesis Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Regulation Of Endosome Size Protein Polymerization Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Negative Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion Regulation Of Early Endosome To Late Endosome Transport	Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Exit From Mitosis Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Protein Polymerization Protein Homooligomerization Negative Regulation Of Cell Death Midbody Abscission Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation ESCRT III Complex Disassembly
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Budding and maturation of HIV virion Macroautophagy Lysosome Vesicle Biogenesis Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Adult body size ( 32376654) Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence symptom count ( 25555482)	Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		13 interacting genes: APP CHMP2A CHMP2B CHMP4A CHMP4B FBXO7 IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2	21 interacting genes: CHD3 CHMP3 CYP4F2 DOCK8 E2F4 EIF2B5 ITGA5 KERA MAPKAPK3 MITD1 NCOA1 NOL4 SLC25A1 STAMBP TGFB3 UFD1 USP54 USP8 VPS4A VPS4B ZNF32
Entrez ID		51652	27243
HPRD ID		15650	12520
Ensembl ID		ENSG00000115561	ENSG00000130724
Uniprot IDs		Q9Y3E7	A0A024R4S0 O43633
PDB IDs		2GD5 2XZE 3FRT 3FRV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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