ATP6V1H and FLACC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATP6V1H	FLACC1
Description		ATPase H+ transporting V1 subunit H	flagellum associated containing coiled-coil domains 1
Image			No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Extracellular Exosome	Outer Dense Fiber Cellular_component Cytoplasm Cytoplasmic Vesicle Sperm Fibrous Sheath Sperm Flagellum
	Molecular Function	Protein Binding ATP Hydrolysis Activity Enzyme Regulator Activity Proton-transporting ATPase Activity, Rotational Mechanism	Molecular_function Protein Binding
	Biological Process	Endocytosis Vacuolar Acidification Regulation Of Macroautophagy Regulation Of Catalytic Activity Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Nef Mediated CD4 Down-regulation Nef Mediated CD8 Down-regulation Insulin receptor recycling Transferrin endocytosis and recycling Blockage of phagosome acidification Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		10 interacting genes: ATP6V1E1 CDKN2B ETHE1 FLACC1 PPP1R12C SNPH SOX9 SPATA2 TANK TRIM14	23 interacting genes: ATP6V1H BLK CRK DISC1 DVL3 FAM90A1 ICA1L INO80B LGALS14 LONRF1 PRPF31 SPG21 SSX2 SSX2B SSX4 SSX4B STK16 SULT2B1 TCL1A TEPSIN TRIM41 TXNDC5 YES1
Entrez ID		51606	130540
HPRD ID		10591	12444
Ensembl ID		ENSG00000047249	ENSG00000155749
Uniprot IDs		A0A024R7U9 A0A024R7X3 B3KUZ7 Q9UI12	A8K8B8 Q96Q35
PDB IDs		6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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