ATP6V1H

Description		ATPase H+ transporting V1 subunit H
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GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding ATP Hydrolysis Activity Enzyme Regulator Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Endocytosis Vacuolar Acidification Regulation Of Macroautophagy Regulation Of Catalytic Activity Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Nef Mediated CD4 Down-regulation Nef Mediated CD8 Down-regulation Insulin receptor recycling Transferrin endocytosis and recycling Blockage of phagosome acidification Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		10 interacting genes: ATP6V1E1 CDKN2B ETHE1 FLACC1 PPP1R12C SNPH SOX9 SPATA2 TANK TRIM14
Entrez ID		51606
HPRD ID		10591
Ensembl ID		ENSG00000047249
Uniprot IDs		A0A024R7U9 A0A024R7X3 B3KUZ7 Q9UI12
PDB IDs		6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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